ID A0A0N0XWQ1_9ACTN Unreviewed; 561 AA.
AC A0A0N0XWQ1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:KPC64027.1};
GN ORFNames=ADL29_13385 {ECO:0000313|EMBL:KPC64027.1};
OS Streptomyces chattanoogensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=66876 {ECO:0000313|EMBL:KPC64027.1, ECO:0000313|Proteomes:UP000037982};
RN [1] {ECO:0000313|Proteomes:UP000037982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL ISP-5002 {ECO:0000313|Proteomes:UP000037982};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPC64027.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGKG01000112; KPC64027.1; -; Genomic_DNA.
DR RefSeq; WP_053923874.1; NZ_LGKG01000112.1.
DR AlphaFoldDB; A0A0N0XWQ1; -.
DR PATRIC; fig|66876.3.peg.2953; -.
DR Proteomes; UP000037982; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046278; P:3,4-dihydroxybenzoate metabolic process; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR012794; PcaR_PcaU.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02431; pcaR_pcaU; 1.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF34; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 2.
DR Pfam; PF01614; IclR; 2.
DR SMART; SM00346; HTH_ICLR; 2.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51077; HTH_ICLR; 2.
DR PROSITE; PS51078; ICLR_ED; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037982};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 19..86
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 80..277
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT DOMAIN 306..366
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 367..551
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT REGION 176..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 59500 MW; 9BA188029E3B1043 CRC64;
MSRPAPTDPS SPPPPPEAVG PLMRSLSVLR ELTAAGGRQA VGDLVRGTGL ARSTVDRVLS
TLARLGYVRT EGRDAVLAPR LLELGNAYLA ACELPDRLGP LADRLADELD ESVSLAVPDG
DGVRFVHQAT RRRAMSLAFR IGDLLPAERG APGALFADAW DADDWRRWRR RRGAAPADAG
FPAVPPRRPG EAPDDASGTG FEARVAAART AGWSQDDQLI EPGLVAVAVP VRDPAGRTVC
AVSVVSHTSR LSADALREAV LPRLRDTVDA MEYALSLTGR PADAPASPHA ASWMRASKQE
LGPEFVESVA RGLTTLTAFG AGRAELPLTA VAEATGLPRA TARRALITLE HLGYVAAGGK
LFRLTPKVLE LGFAHLSGLT LPAIAQPHLA ALVERVHDSA SMAVLSGDDI QYVARVPTVR
IMSVNITLGT RFPAYATSMG RVLLAGLPPA EASARLALTR LEPLTRHTVT DPDRLMTLLE
KVRAEGYALV DEELEEGLRS LAVPVHDRTG RVVSAVNVST HAGRCSPDEA REAVLPALRE
AAAAIEADLR MAGRYVRIPV V
//
