ID A0A0N1FT53_9ACTN Unreviewed; 416 AA.
AC A0A0N1FT53;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KPI02210.1};
GN ORFNames=OK074_5394 {ECO:0000313|EMBL:KPI02210.1};
OS Actinobacteria bacterium OK074.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592327 {ECO:0000313|EMBL:KPI02210.1, ECO:0000313|Proteomes:UP000037991};
RN [1] {ECO:0000313|EMBL:KPI02210.1, ECO:0000313|Proteomes:UP000037991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK074 {ECO:0000313|EMBL:KPI02210.1,
RC ECO:0000313|Proteomes:UP000037991};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI02210.1}.
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DR EMBL; LJCV01000280; KPI02210.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1FT53; -.
DR PATRIC; fig|1592327.3.peg.8090; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000037991; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KPI02210.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037991};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 179..213
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 317..393
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
FT REGION 208..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..240
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 43679 MW; B0057B93E25A0689 CRC64;
MRSTPGRGCA RGVAVGALLA LSYYDISIAY DTAYNPLRPA LLLLVGLVAV FWPPGRWPAV
VTPQLRTAVP ALCGLLVTAD SLLRHRSVPF GPGESTILLC LLFLAVRQCP PGWAVACGLL
DAGALLSMPL RYAPGFSAEA VPYFLVDVLL ALVTASFAAY LRWLEYRRTT AIAETRREER
LAIAADLHDF VAHHVTGILV QTQMARMMAA TPPGPGPGPG PGPGSGTGSG PGPGPGEGPP
LDPVLAGIER AATEALASMR RTVGVLRDAT ASAAERRPVG DLAAVAELVD GFAAPGQKVT
LRRDPAVVDD LPHEVQAAAF RVVQEALTNV RRHAADATEV VVGLRHDERG RLEVTVTDDG
RGGTQLPDAA HGGGFGLVGL TERVTALDGE LYTGPRGDQA YGWEVRALFP PPPHAR
//
