ID A0A0N1FZP9_9ACTN Unreviewed; 506 AA.
AC A0A0N1FZP9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN ORFNames=OK074_3137 {ECO:0000313|EMBL:KPI10606.1};
OS Actinobacteria bacterium OK074.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592327 {ECO:0000313|EMBL:KPI10606.1, ECO:0000313|Proteomes:UP000037991};
RN [1] {ECO:0000313|EMBL:KPI10606.1, ECO:0000313|Proteomes:UP000037991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK074 {ECO:0000313|EMBL:KPI10606.1,
RC ECO:0000313|Proteomes:UP000037991};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI10606.1}.
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DR EMBL; LJCV01000220; KPI10606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1FZP9; -.
DR PATRIC; fig|1592327.3.peg.5073; -.
DR Proteomes; UP000037991; Unassembled WGS sequence.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 2.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR038417; Alpga-gal_N_sf.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR031704; Glyco_hydro_36_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF16875; Glyco_hydro_36N; 1.
DR Pfam; PF02065; Melibiase; 1.
DR PRINTS; PR00743; GLHYDRLASE36.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:KPI10606.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KPI10606.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037991}.
FT DOMAIN 148..216
FT /note="Glycosyl hydrolase family 36 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16875"
FT REGION 418..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 55226 MW; 1B41BC2F38A50C37 CRC64;
MQPCRRTSPH DPDHRLWVLS GPAPSYVLHL DDEDRLRGLH RRPRLTPEQA ASLLERPLPR
RQFEHPADGL LALDTAGAMR YGHAAVQVRF ADGVHDLELS WTGETRTDHE LVLTFADRHY
PLTAEAHFRV HADTDVLERH LVLRHTGTEL PYGETVLSSR RGTTGHHANP WVMLDDGTAS
EEHGRVHSCA LAWSGSWQLT VQRLPTERVA VSAGAGHAPI TTRLSPGTEL RTPVSAAAYT
EGGFGGASRA WHRYLLGHVL PHPGELRPVL YNSWEATEFD VSVEGQSALA ERAAALGVEL
FVMDDGWFGA RTHDAAGLGD WTPNPARFPD GLAPLIDRVH ELGMRFGLWV EPEMVNPDSD
LYRTHPDGVL HHPTRRRTEA RNQLVLNLAR PDVAAWMYDR LDELLTNNDI DLLKWTSTAP
SRKPVGPTPR ATPKPCGPTT CTTSTPSSTG CAPPTRTCAS SPAAAAAPDS TPASWPAPTR
CGPPTTPTPS TAWTSSTASV SSTRPG
//
