ID   A0A0N1G1P1_9ACTN        Unreviewed;       483 AA.
AC   A0A0N1G1P1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=NADP-dependent oxidoreductase domain containing protein {ECO:0000313|EMBL:KPI12106.1};
GN   ORFNames=OK074_2727 {ECO:0000313|EMBL:KPI12106.1};
OS   Actinobacteria bacterium OK074.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=1592327 {ECO:0000313|EMBL:KPI12106.1, ECO:0000313|Proteomes:UP000037991};
RN   [1] {ECO:0000313|EMBL:KPI12106.1, ECO:0000313|Proteomes:UP000037991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OK074 {ECO:0000313|EMBL:KPI12106.1,
RC   ECO:0000313|Proteomes:UP000037991};
RA   Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT   "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT   and OV320.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPI12106.1}.
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DR   EMBL; LJCV01000177; KPI12106.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N1G1P1; -.
DR   PATRIC; fig|1592327.3.peg.4518; -.
DR   OrthoDB; 9153660at2; -.
DR   Proteomes; UP000037991; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43827; 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE; 1.
DR   PANTHER; PTHR43827:SF3; ALDO-KETO REDUCTASE; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037991}.
FT   DOMAIN          17..138
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
FT   REGION          199..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          439..483
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        205..221
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   483 AA;  51350 MW;  8591C52D572E4AAE CRC64;
     MAHTPWPVFG LEDRDAREVR AAVDLGYRRF DAAEGYGTTT DDLATALTDS GVDREHVEIL
     YKFDVRPDET SEELKQRLTS VAEQFGGHLD AVVIHNPDAP EEQVQEAWEV LSELKEEGTV
     SRVGVAGVRP DHADLLADLH DTEPLDVVDF AEVPPETTRE YGSDWGRRLL DTLGGSESLR
     YYKVVRALGE LLGRGYGEGE GRVQDQGQGQ GQVQGQGQGQ GYGPVVPSGV AYPNFPYPNY
     PSPYATSAPS APYPAQFYGA AMPSAAPVQV PAPASVPVPV PTFTEAARRD DDTPLPDGVR
     QLLMPLFEQP EAMRAELLAY GGGGPVDREA VSRWLVEERG FAREELEGIT VPDRVGLRAE
     FRDMKLADVL AAHLGSDPQG QAWAGELGYP LLHDAETWHE VRPALTAVAA PAQGAVRGGS
     TAAPAPLSVA EVAALRSVNS PSGQVGSGTH TDAVTVTSAA VHLSPSASPS PSASPSSAGG
     RNR
//