ID A0A0N1GC40_9ACTN Unreviewed; 331 AA.
AC A0A0N1GC40;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:KPI19826.1};
GN ORFNames=OK074_7749 {ECO:0000313|EMBL:KPI19826.1};
OS Actinobacteria bacterium OK074.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592327 {ECO:0000313|EMBL:KPI19826.1, ECO:0000313|Proteomes:UP000037991};
RN [1] {ECO:0000313|EMBL:KPI19826.1, ECO:0000313|Proteomes:UP000037991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK074 {ECO:0000313|EMBL:KPI19826.1,
RC ECO:0000313|Proteomes:UP000037991};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI19826.1}.
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DR EMBL; LJCV01000052; KPI19826.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1GC40; -.
DR PATRIC; fig|1592327.3.peg.1952; -.
DR OrthoDB; 3467214at2; -.
DR Proteomes; UP000037991; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF109; TRANSCRIPTIONAL REGULATOR LACI_GALR-LIKE SENSOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037991};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 331 AA; 35274 MW; 36149D4E6B560269 CRC64;
MATIQDVAKL AGVSTATVSR ALSGSRPVGA DLTRRVEEAA ARLGYRHNAL AQALRTQRSN
TIGMVVPQIS NPFFPLLVEA VERRLQQDGL ELLLCDSHQD VAVEARRLRT LTDRHVDGII
VSPLHTTASA PALAATAERV RVIQIDRRVD GSTCHWVGID DAAGFGGLVD LLVSHGRRRL
VFVGSEFTNS SARDRAAAFD NSLARHGLRP AAPALLGRFD VAWGLAAAQS LVQGGEFDGV
VCGDDLIALG VMRGLIRAGV RVPEDVAVTG FDDIAFAEIS DPPLTTMRQQ WDVMADEAVR
LLQGGGGGGS LRIAVAPVLQ LRDSTPRSDE E
//
