ID A0A0N1GSI3_9ACTN Unreviewed; 296 AA.
AC A0A0N1GSI3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=6-phosphogluconate dehydrogenase, decarboxylating {ECO:0000313|EMBL:KPI27824.1};
DE EC=1.1.1.44 {ECO:0000313|EMBL:KPI27824.1};
GN ORFNames=OV320_5872 {ECO:0000313|EMBL:KPI27824.1};
OS Actinobacteria bacterium OV320.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592329 {ECO:0000313|EMBL:KPI27824.1, ECO:0000313|Proteomes:UP000037870};
RN [1] {ECO:0000313|EMBL:KPI27824.1, ECO:0000313|Proteomes:UP000037870}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV320 {ECO:0000313|EMBL:KPI27824.1,
RC ECO:0000313|Proteomes:UP000037870};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI27824.1}.
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DR EMBL; LJCX01000027; KPI27824.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1GSI3; -.
DR PATRIC; fig|1592329.3.peg.5174; -.
DR Proteomes; UP000037870; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004849; 6DGDH_YqeC.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR006184; 6PGdom_BS.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR NCBIfam; TIGR00872; gnd_rel; 1.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00461; 6PGD; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Oxidoreductase {ECO:0000313|EMBL:KPI27824.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037870}.
FT DOMAIN 163..296
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
SQ SEQUENCE 296 AA; 31962 MW; 762BA33F28310F39 CRC64;
MTSMQLGLIG LGKMGGNMRE RIRRAGHTVI GYDRNPEVSD VSGLAELVDK LEAPRTVWVM
VPAGEATQSV IDELGGLLQS GDTVVDGGNS RWTDDEKHAK ELGAKGIGFV DAGVSGGVWG
LQNGYALMVG GDVAHVAKVQ PIFDALKPEG PYGYVHAGKV GAGHFSKMVH NGIEYAMMQA
YAEGWELLEK VDSVENVREV FRSWQEGTVI RSWLLDLAVN ALDEDVHLDR LRGYAEDSGE
GRWTVEAAID NAVPLPAITA SLFARFASRQ EDSPQMKMIA ALRNQFGGHA VESAEK
//
