ID A0A0N1GXQ4_9ACTN Unreviewed; 427 AA.
AC A0A0N1GXQ4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Integral membrane sensor signal transduction histidine kinase {ECO:0000313|EMBL:KPI30662.1};
GN ORFNames=OV320_0325 {ECO:0000313|EMBL:KPI30662.1};
OS Actinobacteria bacterium OV320.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592329 {ECO:0000313|EMBL:KPI30662.1, ECO:0000313|Proteomes:UP000037870};
RN [1] {ECO:0000313|EMBL:KPI30662.1, ECO:0000313|Proteomes:UP000037870}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV320 {ECO:0000313|EMBL:KPI30662.1,
RC ECO:0000313|Proteomes:UP000037870};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI30662.1}.
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DR EMBL; LJCX01000021; KPI30662.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1GXQ4; -.
DR PATRIC; fig|1592329.3.peg.1229; -.
DR Proteomes; UP000037870; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KPI30662.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037870};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..273
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 333..420
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
FT COILED 194..222
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 427 AA; 44721 MW; 07946660BEA88700 CRC64;
MNVEAVGRIR EAGTALVRPV APLPRPTRRN LLFDALLALV LAVAATVYAL SAGVGRSYLL
VDGMARVRTG ADTWAGAVVP ALLVTLPLAL RRRFPLAVLW VVLGAGILAP DGEARIVFYS
LVVATYSAIA FSPYRAAIVA GLPPALLVLA SIGDAGVPAV PDRDVPLLVL LPLAMAAYGI
RTWRARADER QTRMAELARE RAAELRRAAE QERARIAREL HDVVTHHVSV MVIQAGAART
VLDAAPAQSR EALLAIEAGG RAAMTELRHA MGLLLMNFGD DRDDIGAVSA DTAPPPGLDR
VEELVARVRA CGLPVELTVT GARLPVPAGI DLAAYRVVQE ALTNTMKHAA GSRATVTIAY
GESDLGIEVT DTGGAPGAAA GTGDGHGLLG LRERLGVYGA TLRNGPAPDG GYRVAALIPL
LPRERTT
//
