ID A0A0N1HLC8_9EURO Unreviewed; 1094 AA.
AC A0A0N1HLC8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Linear gramicidin synthase subunit D {ECO:0000313|EMBL:KPI37785.1};
GN ORFNames=AB675_74 {ECO:0000313|EMBL:KPI37785.1};
OS Phialophora attinorum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX NCBI_TaxID=1664694 {ECO:0000313|EMBL:KPI37785.1, ECO:0000313|Proteomes:UP000038010};
RN [1] {ECO:0000313|EMBL:KPI37785.1, ECO:0000313|Proteomes:UP000038010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 131958 {ECO:0000313|EMBL:KPI37785.1,
RC ECO:0000313|Proteomes:UP000038010};
RA Moreno L.F., Stielow B.J., de Hoog S., Vicente V.A., Weiss V.A.,
RA de Vries M., Cruz L.M., Souza E.M.;
RT "Draft genome of the ant-associated black yeast Phialophora attae CBS
RT 131958.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI37785.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LFJN01000022; KPI37785.1; -; Genomic_DNA.
DR RefSeq; XP_017997748.1; XM_018147872.1.
DR AlphaFoldDB; A0A0N1HLC8; -.
DR STRING; 1664694.A0A0N1HLC8; -.
DR GeneID; 28739645; -.
DR OrthoDB; 2230730at2759; -.
DR Proteomes; UP000038010; Unassembled WGS sequence.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR PANTHER; PTHR43439:SF2; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR43439; PHENYLACETATE-COENZYME A LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000038010}.
FT DOMAIN 83..361
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 578..645
FT /note="Carrier"
FT /evidence="ECO:0000259|Pfam:PF00550"
FT DOMAIN 693..942
FT /note="Thioester reductase (TE)"
FT /evidence="ECO:0000259|Pfam:PF07993"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1094 AA; 119864 MW; 4999E68C5D596ECA CRC64;
MSITETLPPP AATTLTTSNT KQTLQQPPRP PPTKFHTIDG ILKSHIAEGF DGTILAYPAT
PNGTSDFEEY SPKDLDRFVD AAVAKYISSG IEPADPSLPE APVIAVLSPS SLEIVVTIWA
MNRMGYGLLF LSTRLAADAY ARLMELSNCD RLITSSGFER MGQDIAKIRE CKRYPLITRP
DFRHVQNPPV FKREGADPLK ETNKLGWIIH SSGSTGFPKP IFLTNYQCLA NFVKKPGMRA
FCVSPLFHSH ALMELGGAIY LQKPMFLGNY ALPVTTQNLI EGMSVARPDL FNVVPYVLKL
MSERPEGLAE LRKVKLVLYA GSACPDALGD LLVANGVNLV ANYGCTETGF IMSSVRNYDT
DKDWDYCRLE YPIAKHVLMD EVSPGVFECV GLDGLPSKGP SNSDNPPNSF RTKDLFTRHP
DPAKSNYYKY LARSDDRLTL VNGEKVLPLP IEGRIRQDPL VEQAAVFGAG KSVPGVIIFR
SELAANMSDA ELLAGIKPSI DDANAAAESF SRIPEEMIIP MPAGTAYPKT DKFTFIRAQM
YQVFAAQIEA AYAAFEDTLP TPSENLKTLS VPELENFLLD TFRARLSIPL AATTTDIFAA
GVDSLQTARI NSIIRKEIDL GSNASKMSSN VVFEKGTVAA LARHLYSLRT GEVKQATDDV
SLMQSLIEEL SVFAPFTPSS SLSETSGKAT VLLTGATGSL GAYIAASLLS RPNVGQVYCL
VRAKSELDAH LRVLSQISSR GTTLTAAQIS RLVCLPSEFA NPTLAIPEAH YNHLLTNLTH
VIHCAWPVNF TVPLQTFRPA LRGLHNLLQL CLNVKRSQPA KFFFCSSVSV GSNTPKDSTN
AASIGETLIP DLSHAQGTGY GKSKLVGEHI THRAMVTYQQ HGLEARVLRI GQLSGDLAKG
KWNETEAVSL MVQSCLAKGV DCLPALDEEV SWLPVDVCGQ AISDLAFRVD GGSDCNGKRK
REAELVYHTL NPHKIHWTHD FIPALRRTNL LPEFEVLPPQ EWLRRLRESD QDPARNPSIK
LLSFWEEKYG KAQAAVTNEK ETPRTTSSGL TFETSRTVHD APVVGSVTRE VMLEQGQNGY
ISKLVGSWMK TWTA
//
