ID A0A0N1IG53_PAPMA Unreviewed; 3121 AA.
AC A0A0N1IG53;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=superoxide dismutase {ECO:0000256|ARBA:ARBA00012682};
DE EC=1.15.1.1 {ECO:0000256|ARBA:ARBA00012682};
GN ORFNames=RR48_01620 {ECO:0000313|EMBL:KPJ14045.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ14045.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ14045.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ14045.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ14045.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC ChEBI:CHEBI:18421; EC=1.15.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001605};
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DR EMBL; KQ460546; KPJ14045.1; -; Genomic_DNA.
DR STRING; 76193.A0A0N1IG53; -.
DR InParanoid; A0A0N1IG53; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR CDD; cd00305; Cu-Zn_Superoxide_Dismutase; 1.
DR Gene3D; 2.60.40.200; Superoxide dismutase, copper/zinc binding domain; 1.
DR InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR InterPro; IPR024134; SOD_Cu/Zn_/chaperone.
DR InterPro; IPR001424; SOD_Cu_Zn_dom.
DR PANTHER; PTHR10003:SF86; COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE; 1.
DR PANTHER; PTHR10003; SUPEROXIDE DISMUTASE CU-ZN -RELATED; 1.
DR Pfam; PF00080; Sod_Cu; 1.
DR PRINTS; PR00068; CUZNDISMTASE.
DR SUPFAM; SSF49329; Cu,Zn superoxide dismutase-like; 1.
PE 4: Predicted;
KW Antioxidant {ECO:0000256|ARBA:ARBA00022862};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240}.
FT DOMAIN 2930..3062
FT /note="Superoxide dismutase copper/zinc binding"
FT /evidence="ECO:0000259|Pfam:PF00080"
FT REGION 1994..2031
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2170..2231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2322..2352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 670..707
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2170..2209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2210..2231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3121 AA; 355522 MW; D4ED214E5EC5CF48 CRC64;
MKHYLVYEKK GHYVPETDDI EQNTEVIDQG ATTVRPQTTE VLLEVPINET TITNEREKKT
SLTHVKKYRP FSIEYYNEIL HQNIPKSSTK QTETQEKINR FKLPVSNEYD PENLNWNQSI
DQKIRQINSN KDINEEEFIK TENKVYTESF IHDKNKEDYV KEDVKETARK IITESLVKAI
PIREEIGKDI NKELNIENDI RIIKTPSVMM KELKQENELN ENLLDKTSEI NKSVKESVDL
YESIDTKLGI NNYIKPDDER KLFLLQEIEE SIEEGLVKKK STIFENKTKQ ITIRGRQMEK
FAARKVFSIA SETIKNIKRT AESRLSKPLL KIFLLYLINI MITLTRCMSI YSKVYNSSRK
EELESTTKLT KEHQESFKRK LSSADIVQLV SGKPKDLTER MDTVISEFHT KLNINKSQVK
LQDNRRAKSV SKVDKINDNK TFEWISELDR EEREQIKEEI KLATLAAARR VLGRRRSYHN
LTDIENEKID GLTYIAIVES HVYTNRNAIF NDYISRLKKQ VNDVLEITDI NETFATDCTV
GKSYKYSSNQ SELKDAYAKN TEDSLSKDVS IDERQKIEYV ATVTVEHKQI PNTLSTEEDE
KYIEINKLAL NETILTSDLE DREVKQITTK TEDRIEVNET KNSKEAIIPK PIMKKVEFTT
NINEATVNQM NELLNKEQKE SVEITELKEN LSKVNKESKE LNNVQARGVE TIEEITTARH
ETEENQISYA ISNASAAVVE ENKFIAQENT PIVEEVRNEI IKVEVAKEAT ADSHFTEAGT
VTVTDIKEQI PKITEEQEKL SKAQMLNKEY IRQENEVYFE VDVKDGEPYK LLEDKGLLTT
ETGKIIATKM INETYINEEP IEMPQTEVQS EVSAKITTEE SHLESALATS RGMLCEFTTE
TETAVSTEDV KIEKEVAMTK AETNELANAQ IVAIATARQT SEVFDEVQND VEITEITEEL
PTTNLVEENL RKPVIFGKDV LRQISAVFNT IEEDIEKEHL QEEKAVEVIE VNELATAHKL
NYAHIEEKHA ISDHLNIQSS YCEDKNTFEN ECMTEEHALY EEEKRDYYLS QPVCTSVCYY
IEINLEECKI LEKDKILEQL PKISIEENVF GSALSICNST LNEFHTTYIE AELIDKEDLT
LEKAESSEEE NKYFKTLVTC IEICENIEVL LEDTYELIVD KFQEEFATTQ IEPEVFVTAL
TICISISNEI NTIYVEAEFL PDERLPEEKS ELSEEKNNYF NALAVCNEVS QDIELLLEES
NELIIEQLKD EFPSTSTETF VLERTLPLST SILSQIDQEL YEAMNLEIED LRKEEVKVLI
EISKLTLILA ICIAAMEEIY KDLEECTPFT VEEINDEIGN FIEEPFVLIR ILPTCVSILE
HINISHNNAE VLEIQQLPIE NANSTLEVNH FVTILAICTG IVETKITTLD EVNSFKIDEI
LEYKASEYLE PKTFSKTLPK CIATVFILNV PVFEVTVREP ECFEHTTASE SLKMQDLVTA
QITCQSILEQ DEISVNEVEK TSSSYEVEEN YANLSYEDIE VNATYNVSTA IEKQIEPVDV
KIEPTHNKNV ASIQEVNVNK DNTTEIVKSR KKKNINAVSL IKDKVDTKNI KVTAFEENSA
DFESFHIEEL KEDDLINDQI TIIEEPVHLM AKETVTIGRK KANVKQKASN AVYQESNIQS
NENVDACSTS VNIQPTKKCI NNEANVNISI QKAKAKKNEN YQEMSYNLTL TKPQVMNIPV
SETKEETLYV KRREDLKQHY TEEFEEEFNL NLNEDVESGV VIHEITASDE DIEDSINIDN
RNESMDASLE FKSQSETQDE SKDVYETSTL VKRRSKEYDS RQKSAALTIF RKEVFEEDIP
VIEKYDENNI NINVISTYSN NKSECVGKTE TISQSSDFES KSVPENTVNN KRVSKRISKS
NTLALNVGFK EDKRQEVGGR RHTDLEINAS RSQINTIEGS FEKSVKTSSI SQESTTLVSQ
EYHSTIVNNK SKSLSLKTNL KQEETEGSQI EETSESSPEI KSPTEPPTPL TDEYIFRLVA
PLPKSRGTTP VPREPSPEII DKDQSILNKN LVPNIDSVAI ERVVYNPPLP TPLTSPVHSP
TYTKPGLNGG MKRLPRYFKP GLRGGSDRPP ISKEEILEVR KNLSTLTTDI NETLKNIEKY
KKLVEILKQK KAEEESSTMM EEDDTTNKQT KPEEVEDAKD AKENETSEQI TTEKPINEKP
PESNVQTNSQ TDEFVEIKLN NNKTDTMNID IKQDFVNRIE EARIKSYNIK EVTSFEEIEK
EYENIGIVEL APDTAGEESI EKEFNIITED SESEKPKVLI KIERDKEKEK SEDKDDVTSD
EEQKAIDEEV ARLNTDLNTS KEISPIESSP SEADTIKEAH IISLTRVLSS HMLREGLSPD
CQKMKDKFEN EKNIPEEKIK DEDRSWTTFL QKSTNLPTQK LGHFADLQNK FEKQEDIVML
HISEKKFNDV CEFNPHLAVV DNGLVTPKLI GSEPFVEEEL FTTKVTDRNE VRLSPVIKPK
DFNSSPVPWQ ERALADTLGA SNIKVEELTP GDEPQFFLAI PTESKDDGVL KSTVIPLPNP
KQEIPNVDIN EKLIEDRKSE HTVDQLIQEA LIKVDNLNIG AGKNRLIQLL LNNIKNITDS
DIPVEDQLNQ MRKQLDTLEQ VPDIIKETLE NVAGKLHLIN QKEVIEPKVI TAVEANKEEP
QIIKEKAKET KVAKMSAETK GELLVKDKKL FEPQMTHKNR PQQKFGWMKP EPRPIKLFGG
RRWKRPGEEY TEEQIAETIL AHSELIQGKT MGINFMKYEK PPIPLDHLQH SEVFKMIHNT
EETPQKPVEL LRTVIAEADY RELEVLVDFG PKLDQNVLDK TLNMLKSQDG VQEAVYKDGA
IMVETILPST QILDIVTQNS GKRAVLQGFG DTQSAVSMVS SQSCCGTNVL GVVRFQQTRE
GSLIADGCID GLTPGCHGLH VHEVGDLSQG CKSIGEHYNP LSATHGAPND PEHKRHAGDL
GNIVADETGR ATFRIVDNVL KVWDIIGRSV AVTERGDDFG RGTSPESRID GDSGSPVACG
IIARSAGVFQ NPKRICACDG VIVWDEKDRP LAGKGRREET KEQRCCKKET QNDAVKPCCK
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