ID A0A0N1IHA0_LEPSE Unreviewed; 359 AA.
AC A0A0N1IHA0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Putative farnesyl synthetase {ECO:0000313|EMBL:KPI82784.1};
GN ORFNames=ABL78_8202 {ECO:0000313|EMBL:KPI82784.1};
OS Leptomonas seymouri.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leptomonas.
OX NCBI_TaxID=5684 {ECO:0000313|EMBL:KPI82784.1, ECO:0000313|Proteomes:UP000038009};
RN [1] {ECO:0000313|EMBL:KPI82784.1, ECO:0000313|Proteomes:UP000038009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 30220 {ECO:0000313|EMBL:KPI82784.1,
RC ECO:0000313|Proteomes:UP000038009};
RX PubMed=26317207;
RA Kraeva N., Butenko A., Hlavacova J., Kostygov A., Myskova J., Grybchuk D.,
RA Lestinova T., Votypka J., Volf P., Opperdoes F., Flegontov P., Lukes J.,
RA Yurchenko V.;
RT "Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by
RT Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania
RT donovani.";
RL PLoS Pathog. 11:E1005127-E1005127(2015).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI82784.1}.
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DR EMBL; LJSK01000544; KPI82784.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1IHA0; -.
DR EnsemblProtists; KPI82784; KPI82784; ABL78_8202.
DR VEuPathDB; TriTrypDB:Lsey_0544_0010; -.
DR OMA; GKQMRPM; -.
DR OrthoDB; 25272at2759; -.
DR Proteomes; UP000038009; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR GO; GO:1901663; P:quinone biosynthetic process; IEA:UniProt.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 359 AA; 39067 MW; 4F75BAC32B6B0C19 CRC64;
MLNRCLLRLC AAAQSQGSKA LTAEGRPFTL VDREVTAVKD HIQTLVANTQ NDVLDHAGKY
ALAAGGKLMR PALVALMAYA MLPAEVSARL MKEPLGCLDN VTPGTLLPFL RLAEVTELIH
TASLVHDDVI DNSDTRRGRL ALHKVYDAKR AVLAGDYLLA RASFYIATLQ VPRIVILMTT
ALEELTSGEL IQMDGCFDIP RYEQKNFCKT ASLISNSLAS TAVLADPGNE ALEQVAFDFG
KHLGIAFQIV DDCLDITGDE KTLGKPKQAD MKEGIATMPV LLVAQRDAKV DAAVRRRFSE
PGDAEFCIEM VEKEGAVAEA MQCADEHCRL SIEALHKLHP SPARDALEKA LSIVMNRKS
//
