ID A0A0N1IS18_9ACTN Unreviewed; 784 AA.
AC A0A0N1IS18;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Helicase {ECO:0000313|EMBL:KOX52151.1};
GN ORFNames=ADL09_03530 {ECO:0000313|EMBL:KOX52151.1};
OS Streptomyces sp. NRRL F-7442.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519498 {ECO:0000313|EMBL:KOX52151.1, ECO:0000313|Proteomes:UP000037772};
RN [1] {ECO:0000313|EMBL:KOX52151.1, ECO:0000313|Proteomes:UP000037772}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-7442 {ECO:0000313|EMBL:KOX52151.1,
RC ECO:0000313|Proteomes:UP000037772};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX52151.1}.
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DR EMBL; LGEH01000016; KOX52151.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1IS18; -.
DR PATRIC; fig|1519498.3.peg.719; -.
DR Proteomes; UP000037772; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 247..635
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 268..275
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 784 AA; 85372 MW; B6DF4D5BB93FF397 CRC64;
MPSTSEGGPV AAQAQQESAV DSEQDSVRED PAREDSVRDR EIGVEQAHLD HVYRRLEEKI
HEAEFLMHDA AQRGHVGTPG ALAERDAQVF RAGIHLNRLN NEFEDFLFGR IDLLLGKDGK
KGPDGAYTAV EPAEGALRPD GTADIAETLH IGRIGVLDED YAPLVIDWRA PAAAPFYRST
PVDPGRVVRR RVIRSKGRRV LGVEDDLMRP EITARLNGEE LAVVGDGALM AALGQARTHS
MRDIVASIQA EQDQVIRAPA ASVTYVEGGP GTGKTAVALH RAAYLLYQDR RRYAGGILIV
SPTPLLVAYT EGVLPSLGEE GQVAIRAIGS LVDGAEATLY DSPATARVKG SSRMLRVLRK
AARGALEPAG SPTLLRVVAF GRRLELEAEE LAGIRRTVLG GTAPVNLLRP RARRLLLDAL
WHKSGAAARH TDPELAAELR SSFDEDVSSE DSFLAFLDAW WPELTPGAVL AAMADERRLG
RWARRVLNGG EVRKVARSLR REGHSVHDIA LLDELQAIVG TPARPRKRRE QDPLDQLTGL
EELMPQREET QWERAERLAQ ERTEYAHVIV DEAQDLTPMQ WRMVGRRGRH ATWTVVGDPA
QSSWSDPDEA AAARDEALGA RPRRRFELTV NYRNPAEIAE LAAKVLALAM PGSPSPSAVR
STGVEPRFAV VADTLAETVR AEAARLLGLV DGTVGVVVAM NRREEARRWL AGLGDRVVAL
GSLEAKGLEY DATVVVSPAE IADESPAGLR VLYVALTRAT QQLTVVSCER DEPDASGVPD
LLRD
//
