ID A0A0N1K8L3_9ACTN Unreviewed; 354 AA.
AC A0A0N1K8L3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Delta-6 fatty acid desaturase {ECO:0000313|EMBL:KPC84015.1};
GN ORFNames=ADK82_06015 {ECO:0000313|EMBL:KPC84015.1};
OS Streptomyces sp. NRRL S-4.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519471 {ECO:0000313|EMBL:KPC84015.1, ECO:0000313|Proteomes:UP000037987};
RN [1] {ECO:0000313|Proteomes:UP000037987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-4 {ECO:0000313|Proteomes:UP000037987};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPC84015.1}.
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DR EMBL; LGKJ01000024; KPC84015.1; -; Genomic_DNA.
DR RefSeq; WP_053928986.1; NZ_LGKJ01000024.1.
DR AlphaFoldDB; A0A0N1K8L3; -.
DR STRING; 1519471.ADK82_06015; -.
DR PATRIC; fig|1519471.3.peg.1249; -.
DR Proteomes; UP000037987; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR CDD; cd03506; Delta6-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR19353:SF19; DELTA(5) FATTY ACID DESATURASE C-RELATED; 1.
DR PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR Pfam; PF00487; FA_desaturase; 1.
DR PIRSF; PIRSF015921; FA_sphinglp_des; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 74..333
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 39132 MW; 29070BF2F5FD4D2F CRC64;
MPQAAAATVA QHTRDGSESP ESPQAPGSDF APLLKAVRGQ GLLERRTGWY AAGMAANLVA
LGVVVTGMVL LGDTWWNVLL ALPLAVLWTR TAFFGHDAGH AQITGDRKAG RIVGFVHANL
LLGMNEAWWN DKHVRHHANP NHIDKDPDVG VGALVWTQKQ AAQREGFARW LTRNQARLFF
PMLLLEGIAL KIYGFQFLRR QPVRERALSG LLLTCHLALY ATLLLTVMSP GKAVVFALVH
HALFGLHLGM AFAPNHKGME MPDPDGDRWG HLQRQVLTSR NVRGAVLTDW LLGGLNYQIE
HHLFPSMPRP HLRLAQPLVK AHCASIGMPY AETGLVESYR QALQHMHEVG EPLR
//
