ID A0A0N1LHX4_9CAUL Unreviewed; 804 AA.
AC A0A0N1LHX4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=IP78_11440 {ECO:0000313|EMBL:KPF78047.1};
OS Brevundimonas sp. AAP58.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Brevundimonas.
OX NCBI_TaxID=1523422 {ECO:0000313|EMBL:KPF78047.1, ECO:0000313|Proteomes:UP000037838};
RN [1] {ECO:0000313|EMBL:KPF78047.1, ECO:0000313|Proteomes:UP000037838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AAP58 {ECO:0000313|EMBL:KPF78047.1,
RC ECO:0000313|Proteomes:UP000037838};
RA Zeng Y., Feng F., Liu Y., Koblizek M.;
RT "Novel Diversity of Limnic Aerobic Anoxygenic Phototrophic Bacteria as
RT Revealed by High-throughput Strain Identification and Genome Sequencing.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPF78047.1}.
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DR EMBL; LJHU01000087; KPF78047.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1LHX4; -.
DR STRING; 1523422.IP78_11440; -.
DR PATRIC; fig|1523422.3.peg.2805; -.
DR Proteomes; UP000037838; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF79; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF12860; PAS_7; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KPF78047.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000037838};
KW Transferase {ECO:0000313|EMBL:KPF78047.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 281..352
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 408..450
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 568..788
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 804 AA; 85872 MW; A72796D33D94B929 CRC64;
MQHPGRRASD NSSPALPAWA RITVLALTLG LALYVVLFAR ESTRPAREAA VLREQALSRD
VAFGAARLEA DLASARLGLA AARSALTRNP DRPLDAIEAA RAVAPASAFA VLDQADAPRA
VQGAEPGAFG AFGQGELVPA LDRGALLTVS DGAGGRIVAR TPVPGDPRGR LLIVMPAAGV
IATGESDLER RIGVGLGPLI EAGEPIKVEL SSERAIEAVA APVGSTGLHA VAWRPESAGA
AAVISDLWLL VAPLGLGVLV LGLALMQRWR QSRAAKVFAE TEHRFRVAVE AARCGVWEWD
TEADEVIVSD YMAELLGLPE GGSVRAEAVM ERIHPRYREL VQHALLQAST FGSFEVTFPV
PVEGRGARWI DARGQARGAR GEHGFSMIMG VALDITEARR AKAQAQSAEN RLRDGIESVS
DAFALFDRNG RLILSNVAFK DAFGFTDEAL RKGALKDELT RIAALAIKAE RPSAEGRAGA
REVELHDGRV LQLNERFTGD GGTVVTAADV TFIRRQELER QRAADSLRAM VDQLEASQEK
LSLLARKYEI AMTRAEAANQ AKSEFLANMS HELRTPLNAI NGFSEIMAGE MFGPLGDARY
KGYAADILKS GQHLLSLIND ILDMAKIEAG KMTLHYEAVD LVEVCEDATR LMRGKAQEAG
LALTLEAGDL PEVEADYRGL KQVMLNLISN AVKFTPEGGS ITVSVHPMAG DRVRIAVTDT
GIGIAAEDLA RLAQPFEQVE GQHSKTTQGT GLGLALTKSL IELHGGQMRM ESEPGEGTTV
SFDIPVRRPV DQTQAHGQPQ ARAA
//
