ID   A0A0N1NF65_9ACTN        Unreviewed;       404 AA.
AC   A0A0N1NF65;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
DE   Flags: Precursor;
GN   ORFNames=OK074_4421 {ECO:0000313|EMBL:KPI05502.1};
OS   Actinobacteria bacterium OK074.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=1592327 {ECO:0000313|EMBL:KPI05502.1, ECO:0000313|Proteomes:UP000037991};
RN   [1] {ECO:0000313|EMBL:KPI05502.1, ECO:0000313|Proteomes:UP000037991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OK074 {ECO:0000313|EMBL:KPI05502.1,
RC   ECO:0000313|Proteomes:UP000037991};
RA   Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT   "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT   and OV320.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPI05502.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LJCV01000262; KPI05502.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N1NF65; -.
DR   PATRIC; fig|1592327.3.peg.6803; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000037991; Unassembled WGS sequence.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037991};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..404
FT                   /note="exo-alpha-sialidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005878850"
FT   DOMAIN          65..379
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   404 AA;  43006 MW;  DAA27195CBC5031F CRC64;
     MTITSRTATF AAAASLLAGV AFAAAVPASA TGGPPASCTS SVPYTAGENG YDTYRIPAVV
     TTRRGTVLAF AEGRHNSAAD SGDIDVVLRR SYDGGCTWGP MSVVASGDGN TRGNPSPVVD
     PRTGKIVLLT SYNSGAVTEA QIMRGEVTPE QSRRVFVQYS RDDGRSFSDP REITADVKEP
     DWRWYATGPG HAIVLTRGRH AGRLVVPCNY SVAPPVGSSD TGQEGKYYGA HDIYSDDGGR
     TWHIGYVDDV HDGVNNANES TVAQLPDGRL YFNARDQNGT SVGNRLDTYS SDGGETLDRP
     YEVQPTLNDV PVVEGNVLQL AGWHGSLLFS GPSVPTSRRA LSIWSSSDQG ETFSKVLTLS
     SQFAAYSDMV RLGHSTVGIL YETGAVTSYD TVEFRRIPVG DLGE
//