ID   A0A0N1NH77_9ACTN        Unreviewed;       305 AA.
AC   A0A0N1NH77;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Transketolase central region {ECO:0000313|EMBL:KPI09636.1};
GN   ORFNames=OK006_0299 {ECO:0000313|EMBL:KPI09636.1};
OS   Actinobacteria bacterium OK006.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=1592326 {ECO:0000313|EMBL:KPI09636.1, ECO:0000313|Proteomes:UP000037912};
RN   [1] {ECO:0000313|EMBL:KPI09636.1, ECO:0000313|Proteomes:UP000037912}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OK006 {ECO:0000313|EMBL:KPI09636.1,
RC   ECO:0000313|Proteomes:UP000037912};
RA   Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT   "Draft genome sequences for four Actinobacteria strains OK006 OK074 OV450
RT   and OV320.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPI09636.1}.
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DR   EMBL; LJCU01000215; KPI09636.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N1NH77; -.
DR   PATRIC; fig|1592326.3.peg.4260; -.
DR   Proteomes; UP000037912; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR   PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
FT   DOMAIN          2..167
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   305 AA;  32564 MW;  926EBD052F5421BD CRC64;
     MDTMRDRFAP VMTRLLDEDP RVAVVLAEIG KDGFTEARRR HPDRVINVGI REQLLVGAGS
     GLALTGLRPV VHTFASFLVE RPFEQVKLDL GHQDVGAVLV SAAASFDWPA GGFTHMAPGD
     VALLDTLDGW TVHVPGHPDE AEQLLRQAVA AGDDKVYVRL SVQSNAQGLP VDGARFRTVR
     EGHAGVVVAV GPMLDAALAA TEGLDVTVLY AATVRPFDGQ TLRRATEAAG TDVVLVEPYL
     AGTSTAAAGD ALADVPHRVL GLGVRRRELR RYGTVDEHLT AHGLDEGSLR ERIGGFLSAS
     DRPRP
//