ID A0A0N1NR82_9ACTN Unreviewed; 430 AA.
AC A0A0N1NR82;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Phthiocerol/phthiodiolone dimycocerosyl transferase {ECO:0000256|ARBA:ARBA00013449};
DE EC=2.3.1.282 {ECO:0000256|ARBA:ARBA00012866};
DE AltName: Full=Acyltransferase PapA5 {ECO:0000256|ARBA:ARBA00033407};
DE AltName: Full=Phthiocerol/phthiodiolone O-acyltransferase {ECO:0000256|ARBA:ARBA00030465};
DE AltName: Full=Polyketide synthase-associated protein A5 {ECO:0000256|ARBA:ARBA00032317};
GN ORFNames=OV320_0504 {ECO:0000313|EMBL:KPI23557.1};
OS Actinobacteria bacterium OV320.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592329 {ECO:0000313|EMBL:KPI23557.1, ECO:0000313|Proteomes:UP000037870};
RN [1] {ECO:0000313|EMBL:KPI23557.1, ECO:0000313|Proteomes:UP000037870}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV320 {ECO:0000313|EMBL:KPI23557.1,
RC ECO:0000313|Proteomes:UP000037870};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 a mycocerosyl-[mycocerosic acid synthase] + a
CC phenolphthiocerol = a dimycocerosyl phenolphthiocerol + 2 holo-
CC [mycocerosic acid synthase].; EC=2.3.1.282;
CC Evidence={ECO:0000256|ARBA:ARBA00000625};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 a mycocerosyl-[mycocerosic acid synthase] + a phthiocerol =
CC a dimycocerosyl phthiocerol + 2 holo-[mycocerosic acid synthase].;
CC EC=2.3.1.282; Evidence={ECO:0000256|ARBA:ARBA00000026};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 a mycocerosyl-[mycocerosic acid synthase] + a phthiodiolone
CC = a dimycocerosyl phthiodiolone + 2 holo-[mycocerosic acid
CC synthase].; EC=2.3.1.282; Evidence={ECO:0000256|ARBA:ARBA00001907};
CC -!- SIMILARITY: Belongs to the acyltransferase PapA5 family.
CC {ECO:0000256|ARBA:ARBA00006558}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI23557.1}.
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DR EMBL; LJCX01000032; KPI23557.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1NR82; -.
DR PATRIC; fig|1592329.3.peg.2013; -.
DR Proteomes; UP000037870; Unassembled WGS sequence.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR031641; PapA_C.
DR PANTHER; PTHR28037; ALCOHOL O-ACETYLTRANSFERASE 1-RELATED; 1.
DR PANTHER; PTHR28037:SF1; ALCOHOL O-ACETYLTRANSFERASE 1-RELATED; 1.
DR Pfam; PF16911; PapA_C; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000037870}.
FT DOMAIN 204..392
FT /note="Phthiocerol/phthiodiolone dimycocerosyl transferase
FT C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16911"
SQ SEQUENCE 430 AA; 46120 MW; 3E5E15E743E33CD2 CRC64;
MRRALCPVET LYVGQRSRAV LSCTLRGRLD IEALSAAFDA VTEAHPSLRT RIVPDGEGFA
LDLLDEAARP RLSTRTGAAE DAYATELNTP LSVGGPLSRA VLVSAPEGDG HLFVLSVDHT
VVDGHSGIAL HNEIWERYRA LAEGEERPGA ADGTPGWAVP VSELLPAVDE AATTAYLERR
VDEARRHPAE LVAYDVTDPS AVEGRIEVCR LTLDEERTGR LRRTARTAGV TVHALVAAAL
LTTARRRLPG GEPRALRCLS PVDLRSRLSP PVPALVMVPA VTSHLQALDV APESDPVELA
RTVHSRLGEF VAGDGPYHEM RITPEIPRNP TLQLATVIAT NMGVVPGPRL PEGLEATDVR
LVPAREQYFP AAGRSPVMAC VVSYEGRLAI EFPYFTACFS PEFVRAFRDE VGAVLDACAT
AVEPVPTAAG
//
