ID A0A0N1P921_LEPSE Unreviewed; 816 AA.
AC A0A0N1P921;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=ABL78_8263 {ECO:0000313|EMBL:KPI82725.1};
OS Leptomonas seymouri.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leptomonas.
OX NCBI_TaxID=5684 {ECO:0000313|EMBL:KPI82725.1, ECO:0000313|Proteomes:UP000038009};
RN [1] {ECO:0000313|EMBL:KPI82725.1, ECO:0000313|Proteomes:UP000038009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 30220 {ECO:0000313|EMBL:KPI82725.1,
RC ECO:0000313|Proteomes:UP000038009};
RX PubMed=26317207;
RA Kraeva N., Butenko A., Hlavacova J., Kostygov A., Myskova J., Grybchuk D.,
RA Lestinova T., Votypka J., Volf P., Opperdoes F., Flegontov P., Lukes J.,
RA Yurchenko V.;
RT "Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by
RT Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania
RT donovani.";
RL PLoS Pathog. 11:E1005127-E1005127(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI82725.1}.
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DR EMBL; LJSK01000575; KPI82725.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1P921; -.
DR EnsemblProtists; KPI82725; KPI82725; ABL78_8263.
DR VEuPathDB; TriTrypDB:Lsey_0575_0020; -.
DR OMA; CFNTRIN; -.
DR OrthoDB; 161947at2759; -.
DR Proteomes; UP000038009; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF12; LEUCINE-RICH REPEAT PROTEIN (LRRP); 1.
DR Pfam; PF13306; LRR_5; 1.
DR SMART; SM00367; LRR_CC; 4.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 18..53
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 784..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..816
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 89055 MW; E5267FDB95BA53BB CRC64;
MSHLIDVNNI RINAHYQCAY CMNPVSNAMR SKQCRHHICG DCAALCTDRC PWCLCRTHWR
DAPAFNAEVQ AAVEEELLQC TLQQLRKAYA YMGETTLRQV ALSFLDTEKR EANVGEMMAY
LSEMRKGTYF TPPSPGGMVP KKRRVLTCGD ESELQSLENK RLIRSLIITD FDFWDTKQLR
EFAELQVLRL QGCRRIRDLS GVSGLRHLTM FNAAGTGLCN LRGLERCMSL ETVIVRGCTR
VASIAPLSQH ACLRTLHCGG TDVANIEAIA SCPRLEVASF DGCSQLSDLS PLAGLTKLRE
ISVATTKVTS LEPLRGGSAT LERVVIDNCV GLSDLSPLRG AAHLKVLHAN NTGLCSLYRC
GKALLSSVEQ LHLRDCDGIH SISDLVAAKN LRVLDIGNTG VSRLEYLVNC VGKLEELNIE
GCRSISDVSF LSSATQLKTL RASDSGIRSI SALHSCSSTL ECVSVGKCVE VIDFTALADA
PLMSELVLRG TYVANLNFLA LCSSLQVLDC AECAHIDDLS ALRTATRLRE AVFSGTRAND
LSPLSKCPQL EVVDFRNCRD ITDISALERA VNLREAIFSN TNVNDLSPLS KCPQLEVVDF
RNCTALSTIR PLVGCTELRR VIFANTSIAS VAALHRSKRI EVADFSFCRK LSDLSPLVES
TELKMLNVEH TAVNSIAALS DSPQIEMVNV AFCEQIEDVT PLMNCSHLWS VKLQGTRVSD
VSPLVTCKKL EVLDICDCPG ITDVSCLLRA KELSSLYVHG SGVRDIGSLR FNYDVKVVGL
PAPGPSASST GSSDMQKKTP PLKRNSLKAS GTCSSM
//
