ID   A0A0N1PCT4_LEPSE        Unreviewed;       981 AA.
AC   A0A0N1PCT4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=ABL78_3348 {ECO:0000313|EMBL:KPI87551.1};
OS   Leptomonas seymouri.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leptomonas.
OX   NCBI_TaxID=5684 {ECO:0000313|EMBL:KPI87551.1, ECO:0000313|Proteomes:UP000038009};
RN   [1] {ECO:0000313|EMBL:KPI87551.1, ECO:0000313|Proteomes:UP000038009}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 30220 {ECO:0000313|EMBL:KPI87551.1,
RC   ECO:0000313|Proteomes:UP000038009};
RX   PubMed=26317207;
RA   Kraeva N., Butenko A., Hlavacova J., Kostygov A., Myskova J., Grybchuk D.,
RA   Lestinova T., Votypka J., Volf P., Opperdoes F., Flegontov P., Lukes J.,
RA   Yurchenko V.;
RT   "Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by
RT   Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania
RT   donovani.";
RL   PLoS Pathog. 11:E1005127-E1005127(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPI87551.1}.
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DR   EMBL; LJSK01000082; KPI87551.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N1PCT4; -.
DR   EnsemblProtists; KPI87551; KPI87551; ABL78_3348.
DR   VEuPathDB; TriTrypDB:Lsey_0082_0040; -.
DR   OMA; LFRLPNF; -.
DR   OrthoDB; 170326at2759; -.
DR   Proteomes; UP000038009; Unassembled WGS sequence.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
FT   DOMAIN          25..313
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
SQ   SEQUENCE   981 AA;  108108 MW;  08BCA67181E0509F CRC64;
     MQCGEASEAL GVEVYRLVPL GGSMPYVVEC MTTYDDLLFV GTHNSKLVAY RIQTDHGKGD
     SPYSGSESST SSSLMLLQEV SSTRRHPVRA LTVVGDHYLL ALIDDTIVLY HFHHDPSQPF
     QLREVTAMTG LKETISFHVK RHRGTLSLVV LQRRRLTIYE ATAAHMEFLL KETVALPDGV
     RTIGWLGRSF VLGGRKEYFL YHASSSSSTA LYPTPRSGAI PFVLPMTPIP EVLIAGEGGG
     MRALLSDGSE VPGGLRVCWT SPPVDMIYEH PYVVSQHSTG PHTVQIRLPL LTTLEETAVK
     NKSCLVQCIA VPKLAKMSQC WWTDYDCPMP TASTNINALA RHPIVVADTS NRLSLLARTP
     VAAQVEKLAA RSWFAVADLL CQLCPHEVPA DALKRVVAAG AVHRFVHLKD YAGCFHELSK
     VEADPRLAVR LFPGFSPPED AANCPPLPIA PPPGVAHAAL PPLVEYLRSR RAAILQQGKT
     FLTTETARAQ LMCVDRALVL AWCTMNEEAP LLALLQAESW CNVADTVALL QEHEQWVALT
     VFLEVHGEYE RTADELARLV GAGGAEEVAR KTLPTEVIQA LHRFFTEHSV LPTSDEVYLP
     QGTIQSWAAA EKKDSAPSKN RAVTTALIGM SAALTFFRRQ ALPSQQKLFA RHLTWVLGCV
     PPEIGLRIFF STQNVQQYAV VLQLLQGYAE MPGGTSKQLL LVSYLHLLFA DARARVSEEA
     LYEQYYRGLA ELLFTEAPST ASLSEETRQR CRYRLDKFLL TSSHVNLDAA EQYFSADSIK
     AQCVPEQALI YRRQGAHRKA VNMFLGEADD MAGAVAYARS ASSEGNGDAF TALLELLLKP
     LQGPPRLEEA LTILDTCDGV DAASVLPMLP DELPLAQLSR FLMHAFRNTA TAYHMSAIDS
     SVLNAKLMLA QETCVRERSR SALLEHDTVC PVCRRKLRPD TVLAVYPNGV LVHHGCVRDE
     CVCPVTHRDS RYDAYSLLED L
//