ID A0A0N4SUI1_MOUSE Unreviewed; 766 AA.
AC A0A0N4SUI1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=V-set and immunoglobulin domain containing 10 like {ECO:0000313|Ensembl:ENSMUSP00000144692.2};
GN Name=Vsig10l {ECO:0000313|Ensembl:ENSMUSP00000144692.2,
GN ECO:0000313|MGI:MGI:1922940};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000144692.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000144692.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000144692.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000144692.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000144692.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_001277245.1; NM_001290316.1.
DR AlphaFoldDB; A0A0N4SUI1; -.
DR ProteomicsDB; 322839; -.
DR Antibodypedia; 71769; 8 antibodies from 4 providers.
DR Ensembl; ENSMUST00000203769.2; ENSMUSP00000144692.2; ENSMUSG00000070604.6.
DR GeneID; 75690; -.
DR KEGG; mmu:75690; -.
DR AGR; MGI:1922940; -.
DR CTD; 147645; -.
DR MGI; MGI:1922940; Vsig10l.
DR VEuPathDB; HostDB:ENSMUSG00000070604; -.
DR GeneTree; ENSGT00940000162314; -.
DR OMA; MSGSFWS; -.
DR OrthoDB; 4605849at2759; -.
DR BioGRID-ORCS; 75690; 0 hits in 5 CRISPR screens.
DR ChiTaRS; Vsig10l; mouse.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000070604; Expressed in esophagus and 65 other cell types or tissues.
DR ExpressionAtlas; A0A0N4SUI1; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44427; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19; 1.
DR PANTHER; PTHR44427:SF5; V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE; 1.
DR Pfam; PF13895; Ig_2; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|ProteomicsDB:A0A0N4SUI1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..766
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012655664"
FT TRANSMEM 661..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 187..279
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 287..372
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 766 AA; 80947 MW; 4016C4A9ECB683B9 CRC64;
MGLSWALLPF LLLDSQDPDK DSGLPFLVKT PASQISVQTP DTKVPTKASG SKLSLEHHNL
EPGSKISSEI YQAASFPQQV GGPLAVLVGT TIRLPLTPVP SSSPPAPLVV WRRGSKVLAA
GGLGSQAPLI SLDPMHQARL RFDQIRGGLE LTSARLDDAG VYTVEVIRGG VSQQIREFVV
GVFEPLPQLS VQPRAPETEE GAAELRLSCV GWNPGSGKLS WSRDGRALGT SDPEGAEPPR
IRTERDQLLI SRPVRSDHAR YTCQVRSPFG HTEAAADVSV FYGPDAPVIR VSSDRDASPA
LYVTAGSNVT LHCSAPSRPP ADIAWSLADP TEAAVPAGPR LLLPAVGPGH GGAYACIAAN
PRTGHRRRSV FNLTVADLPP GAPQCSVEGG PVDRSLRFRC SWPGGVPAAS LQFQGLPEGV
RAGPVPSTLL VTVPARPELS GVAVTCLARH LVATRTCTII PEAPQEVLLQ PIVEETQPGD
VVVALEVTGC PPPSRASWAR QGRPLAPGGG GRLQLSQDGR KLLINNFSLD WDLGNYSVLC
SSALGAGGNQ ITLTGPSISS WRLQRAQEAA VLTWDVERGT LLTGFHIQAW TDSSEVDRVT
MSRDWVSLLI LGPQERSAIV PLPPRNPGTW AFRILPILGS LPGTPSQSRV YQAGSDLSPG
AIAGIVLGSL LGLALLAGLL ILCICCLRRY PGRASVKKQH SLTLAPVLTP PAKKIQSLTP
VQTPRPLPIK TKMQSPHPAK AQQVISPSPT LCPGGSPWTV RAATQV
//
