ID A0A0N4SXJ6_BRUPA Unreviewed; 616 AA.
AC A0A0N4SXJ6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=ANK_REP_REGION domain-containing protein {ECO:0000313|WBParaSite:BPAG_0000040201-mRNA-1};
GN ORFNames=BPAG_LOCUS403 {ECO:0000313|EMBL:VDN81589.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000040201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000040201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN81589.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAD01000017; VDN81589.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4SXJ6; -.
DR STRING; 6280.A0A0N4SXJ6; -.
DR WBParaSite; BPAG_0000040201-mRNA-1; BPAG_0000040201-mRNA-1; BPAG_0000040201.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08310; Death_NFkB-like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR PANTHER; PTHR46680; NF-KAPPA-B INHIBITOR ALPHA; 1.
DR PANTHER; PTHR46680:SF3; NF-KAPPA-B INHIBITOR CACTUS; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00531; Death; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00005; DEATH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 281..313
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 361..393
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 394..426
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 524..613
FT /note="Death"
FT /evidence="ECO:0000259|SMART:SM00005"
SQ SEQUENCE 616 AA; 67432 MW; 7A91D6C1CE2FDACA CRC64;
MHITCTSISS TIFSNIFLSI PISFSISLSV NQPVIVTVNL LTADFRPHYL IITTQQSIVH
IAESTHKFEN LYITRPTKTV EKDLIQPAKT NQQCTPLKVI EVSHNIVRNT KETIWLLLSK
PVANVSISIA IGNRMLPVER LKTHDKLVIF SLPILVIPDK VDKTSPATKS FKILMRNDTQ
QLELPMQVHV SATSNASDTA EIVDKEALIA SLFEFAAEGE PLALVKPLVT LIGTPDNDGC
NALHVAARNK QNFALKTILS VLCEYSSEAE RQRILNAPNV RGQTALHCAV RAGDADCVHY
LISAGAKRNV VDNNLDTVAH YLGEAYNDAI YKEILETSSS EEVESGVEIN RENILAKKNC
YGYTPAHVAV KKLKLSLLEA LIEAGAPVDI PDNNGETPLL TALYMNDADA ASLLAQHNCD
VNVVSNCGDT PLKIACKKKN LVMIGCLLDA GSTMDSLGTG DGRPIEADDE DVQRILNGER
VEAPSVYAQD DPGEQGINEL QSEESISTAT STDAATSYRL RTLKDDVSCL DYLTRLRLSK
ILDVEDKWTI LADHLGCGHM VEFIRVCLDD SSSPTMMLLD QYEQVPNANL STVKQSLEDM
GETLGVRLIQ AGNEQQ
//
