ID   A0A0N4SYQ9_BRUPA        Unreviewed;       654 AA.
AC   A0A0N4SYQ9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=All-trans-retinol 13,14-reductase {ECO:0000313|WBParaSite:BPAG_0000087901-mRNA-1};
GN   ORFNames=BPAG_LOCUS880 {ECO:0000313|EMBL:VDN82066.1};
OS   Brugia pahangi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000087901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BPAG_0000087901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN82066.1, ECO:0000313|Proteomes:UP000278627}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC       CrtISO subfamily. {ECO:0000256|ARBA:ARBA00005855}.
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DR   EMBL; UZAD01000050; VDN82066.1; -; Genomic_DNA.
DR   STRING; 6280.A0A0N4SYQ9; -.
DR   WBParaSite; BPAG_0000087901-mRNA-1; BPAG_0000087901-mRNA-1; BPAG_0000087901.
DR   Proteomes; UP000038020; Unplaced.
DR   Proteomes; UP000278627; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR46091; BLR7054 PROTEIN; 1.
DR   PANTHER; PTHR46091:SF3; BLR7054 PROTEIN; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   654 AA;  74949 MW;  682A97E929061ED3 CRC64;
     MTLCCDSEMS LTTVDRFPPS EMVLVEMYVI LAITSLFFFI SLKMLKRGSD INNCFRKMIC
     TGKSVDPPLS TEQIYNILRN RFNPSIVNEK WDVIVIGSGL SGLTVAKILA TAGRKVLVLE
     QHDRAGGSCH TFKLDKYEFD VGNTSKMLKS ALLKSKIVKS LHYVQDMYPG KELYRICSAI
     TDSQVHWQKM EEPFDTIIIG ERYYGRKTGN SMHFRDQLKL WFSEEADSIH SYFDFVLKCL
     NINLWWLTGV KHLPLFFVRL LSKFSLINFF TNLFKYCELN LIDVMKSYGL SDDVKAIISY
     YFVNYGIPPN RASFLQHNLF LMENGYYPIG GAAFLIASIV RSIQNFGGKV IVQADVQEIV
     FNSGRVNGVK VKHGSFEYII QTSLVVSTAP IIKTFNELIP QNIARNSVMF KRVNELNSLE
     TVPVGGFQAY IGLSGTQNNL RLPSNNFFWY KNSNPYEFDH YLSLSSSEAM EYGCPAQMFI
     CFPSAKDPTW DERNPGTSTC QLISIANPAW FEEFKDTSKK NSIKRLNRAE YTELKHVIGE
     LMLSQFLKLF PNLKSHIAYV EFSTPLTQQY YMRNAYGEYY SLTQQIDRFK LKFWSELRCK
     TDLPGLYLSG QDVLFCGIAS VLYSGLITAG NILERNLLKD LKEAYNEQMD CDRK
//