ID A0A0N4T4A8_BRUPA Unreviewed; 322 AA.
AC A0A0N4T4A8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ion channel {ECO:0000313|WBParaSite:BPAG_0000303801-mRNA-1};
GN ORFNames=BPAG_LOCUS3008 {ECO:0000313|EMBL:VDN84194.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000303801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000303801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN84194.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR EMBL; UZAD01000653; VDN84194.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4T4A8; -.
DR WBParaSite; BPAG_0000303801-mRNA-1; BPAG_0000303801-mRNA-1; BPAG_0000303801.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR PANTHER; PTHR11003:SF90; TWIK FAMILY OF POTASSIUM CHANNELS; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 47..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..102
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 160..231
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 322 AA; 36821 MW; 3B605BBBF8BB6D82 CRC64;
MSVIYFPTEI ERIAIHHVDN VTRVLFEAFD THYITASHLR SKEEYNWTFT TALFFTATLL
TTIGYGNLVP VTFQGRMFCI VYALFGVPLI LITVADIGKF LSENIIWLYA KYVPKKRCKE
KKIVCITSVV GEISGTVKDQ LLQFGLEQYV SIPILLIVGT LLGYITIGAV LLALWEHWDF
FSGFYFSFIT MTTVGFGDIV PVKQEYFLFD LFYIVVGLAI TTMCVDLVGI QYIRKIHYFG
RAIKDARYAL VNVGGRMVHV PDLMRYASVL HQKYGQKRQG HQIRLKGAYT PEDLPLIRYI
DYGSLASEDS RIKHVSSKIQ TR
//
