ID   A0A0N4T6F5_BRUPA        Unreviewed;       304 AA.
AC   A0A0N4T6F5;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Tyrosinase_Cu-bd domain-containing protein {ECO:0000313|WBParaSite:BPAG_0000378801-mRNA-1};
GN   ORFNames=BPAG_LOCUS3756 {ECO:0000313|EMBL:VDN84942.1};
OS   Brugia pahangi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000378801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BPAG_0000378801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN84942.1, ECO:0000313|Proteomes:UP000278627}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAD01001306; VDN84942.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4T6F5; -.
DR   STRING; 6280.A0A0N4T6F5; -.
DR   WBParaSite; BPAG_0000378801-mRNA-1; BPAG_0000378801-mRNA-1; BPAG_0000378801.
DR   Proteomes; UP000038020; Unplaced.
DR   Proteomes; UP000278627; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF84; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..304
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033230712"
FT   DOMAIN          172..189
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
SQ   SEQUENCE   304 AA;  34736 MW;  00347A5EED604AC6 CRC64;
     MKLFCCISTI LFLATFGQEP TFMQNCDEAP TPEARHVCLT LQQMARNSRR EMITNQITLP
     LPPAFLQPAP LDPYARGQVA SHPYDCMTIT CLCPFFQASL IIYFRLGSIG PRNQCILPDG
     QLLTMAYRKE YRMLTEDERL RFFNAMAILK QSGEYDRMSY EHQLVGQGSG AHSGPGFLPW
     HREFLKRFEI ALRLIDPKVS LPYWDSVIDQ YLPDPRDSVF FSPYFIGETD GYGNVVTGPF
     AYWSTIDGRT AILRALGEKG KLFTEYDIID IISQVSVEQV MAYTAPLNGM LKAFQIDQSY
     IYFD
//