ID A0A0N4TJM7_BRUPA Unreviewed; 401 AA.
AC A0A0N4TJM7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Magnesium transporter NIPA2 {ECO:0000313|WBParaSite:BPAG_0000851001-mRNA-1};
GN ORFNames=BPAG_LOCUS8472 {ECO:0000313|EMBL:VDN89658.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000851001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000851001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN89658.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NIPA family.
CC {ECO:0000256|ARBA:ARBA00007230}.
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DR EMBL; UZAD01013135; VDN89658.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4TJM7; -.
DR WBParaSite; BPAG_0000851001-mRNA-1; BPAG_0000851001-mRNA-1; BPAG_0000851001.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF91; SPICHTHYIN, ISOFORM B; 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 401 AA; 44213 MW; 030B493C768357A8 CRC64;
MNAHIFHQSV PMKKFKSSTK EAMSEKAAYF MMNFSVENEI DGNANGSAED FYSFLSTYPL
LDFYIGLSLA ISSSLFIGSS FIIKKKALIK LAQVDCTHRA SEGGFGYLRE WLWWFGVLTM
GTGEACNFAA YAFAPASLVT PLGALSVIVT AVLSSKLLKE RLNLLGKIGC AVCLLGSTVI
VLHSPKEEEV SNMADLALKM RNAGFIFYVV AVILVSLVMI IYVAPRLGRS NILVYIFICS
IIGSLSVLSV KGLGLAIKET IGGKQQLTNF LTWFWLVAVI LCVSIQLIYL NKSLDMYNTS
MVTPIYYVFF TTFVILASSI LYKEWSRLGA SDVLGNVVGF LITIIGIFQM QLFRDVNITL
RHLRMLIHKP STDATFETAN SATSLVDDLP SDAANPQQIY T
//
