ID A0A0N4TM57_BRUPA Unreviewed; 873 AA.
AC A0A0N4TM57;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Protein ECT2 {ECO:0000313|WBParaSite:BPAG_0000951101-mRNA-1};
GN ORFNames=BPAG_LOCUS9473 {ECO:0000313|EMBL:VDN90659.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000951101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000951101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN90659.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAD01013157; VDN90659.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4TM57; -.
DR WBParaSite; BPAG_0000951101-mRNA-1; BPAG_0000951101-mRNA-1; BPAG_0000951101.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:2000431; P:regulation of cytokinesis, actomyosin contractile ring assembly; IEA:InterPro.
DR CDD; cd17732; BRCT_Ect2_rpt2; 1.
DR CDD; cd01229; PH_Ect2; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 3.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR026817; Ect2.
DR InterPro; IPR049395; ECT2_PH.
DR PANTHER; PTHR16777; PROTEIN ECT2; 1.
DR PANTHER; PTHR16777:SF2; PROTEIN ECT2; 1.
DR Pfam; PF21242; ECT2_PH; 1.
DR Pfam; PF12738; PTCB-BRCT; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00292; BRCT; 2.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000278627}.
FT DOMAIN 132..203
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 379..569
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
SQ SEQUENCE 873 AA; 98764 MW; 4E34D7B52499A8B8 CRC64;
MDGEGSVLSS EVAASLLSLE VTEIFTDREN TVARSASQIR RVNRVCVVGV ARSNTEVTDL
LKNHFGIELL ESEDGYEFTK DTGITFLCSE FTDCRWFKYL NSCQKPIIGP AIIRKRAVDG
KPLLVPRPNR PLYTDTMSGV RIALSGLSTK NCREAVDLVH FMGGSAQRVF SASTTHLITD
AARGKTYRMA VSIGCRVMHL DWLRAAWAAR NSIQISVTTI DFMNKYMVEP FCGLSLWFVA
YDEKDLTEMK EKTVENKGKV AGNQKQATHI VVSTSLDAKV EGCDAKQHLV SGEWFWISVQ
LNCCANETIY KWKGQRTKQN STLSPNTAEL ANRARKSVSK SSMEVLDSSN CSALPDYSEH
LLSTDDSEIL NSSPRKLNKR YAVCKEMLET EENYLRALKI VVQVFKEPLE AQLPNLDSGL
LTKAEISQIF AKIPPLIDVH ENICRTLQSY IMHWMNERLI GKVWLDHAAE LTPVYKAFIN
NYDTAIQTLN ECDQSKPKFH AFLKAAESRM ECQRNSLPDL LVRPVQRLHS VVLLLKAILE
KTDRKNPDNA YLIKAKRAVE AALTEANESR RQTDSYAMIF KLSSEIERCP ADILSSARTL
KTELHVLSLG GEDEWAKTRN KRMAIFLFND LIEIVKVRTG NDDSNTPTRR SFSNYSLTRQ
LSFSVLRHGK KKYKHHQQYM LASIRRIQSL VHADINGVFV LSFRVSQGED FWVAQCLENQ
EGELEKFLRE VADQVYKLVG RNTLVEKVDF DEDPSSLGVK ENITTIKKAL NHAVRNPFGG
YQSLGTPRAR PQSQFRRAMS TMHLSISNTL SRLHSRSNLH PVDESFERTS PDGRTHTTGF
TIPTRGFRQM LSTSTFLPSL GRRDSIFSHS IKE
//
