ID A0A0N4TMB9_BRUPA Unreviewed; 465 AA.
AC A0A0N4TMB9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=COP9 signalosome complex subunit 3 {ECO:0000256|ARBA:ARBA00014878};
GN ORFNames=BPAG_LOCUS9542 {ECO:0000313|EMBL:VDN90728.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000958001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000958001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN90728.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN3 family.
CC {ECO:0000256|ARBA:ARBA00007084}.
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DR EMBL; UZAD01013159; VDN90728.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4TMB9; -.
DR WBParaSite; BPAG_0000958001-mRNA-1; BPAG_0000958001-mRNA-1; BPAG_0000958001.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10758; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR10758:SF1; COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Signalosome {ECO:0000256|ARBA:ARBA00022790}.
FT DOMAIN 209..382
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 465 AA; 52993 MW; 15DEF6E70AAD7117 CRC64;
MSGSLDVFVK SVMGLTVSAS WRELADLHRK AIYDVLERNI SHLDSVLETL TIDRYSMSVA
SILLVKMNQI YTENVKDRFE RTLSQLESMV PFFDSMQISF IPDIYVLLFR KVYEYCLLQI
NKPARGIMLL SNAISVLVKE ERDILTSLHP CLFCLCLKAR IHDPAMPFLH LAVPKIFKET
TNQTGPYMDP KWVVLYFYYG GLLYAVLGRY EEAFAMMQKA CCIPAIAPSA IMLRAYKTYV
LLSLLLHGKI LRLSNYRSPV ITRSIIPLCP DYSALERICD NEEENFDKAS AILEYLETHY
ATFEKDKTVG LVKLVVRSIR ENSVKRLTEC FISISLSDVA RRCHLDDSDH AEFYLREMNK
NGKINVRIDK KQGVVYFDEM KTEADERKVD KAANSIYTLD ALMKQFDDRI RVNPSYISRV
GRPLARGVPA VPPDEGLGHP GSIFMPNVNV GDIESAAGRP MDMVD
//
