ID   A0A0N4TMK6_BRUPA        Unreviewed;       848 AA.
AC   A0A0N4TMK6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=CNH domain-containing protein {ECO:0000313|WBParaSite:BPAG_0000968201-mRNA-1};
GN   ORFNames=BPAG_LOCUS9644 {ECO:0000313|EMBL:VDN90830.1};
OS   Brugia pahangi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000968201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BPAG_0000968201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN90830.1, ECO:0000313|Proteomes:UP000278627}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAD01013161; VDN90830.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4TMK6; -.
DR   STRING; 6280.A0A0N4TMK6; -.
DR   WBParaSite; BPAG_0000968201-mRNA-1; BPAG_0000968201-mRNA-1; BPAG_0000968201.
DR   Proteomes; UP000038020; Unplaced.
DR   Proteomes; UP000278627; Unassembled WGS sequence.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..848
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033720801"
FT   DOMAIN          44..305
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
SQ   SEQUENCE   848 AA;  96628 MW;  CBFC62EC0DBC98EB CRC64;
     MSISHGCILI FISKLILHNF HSDMVDEYYR LTDVFETFSF LAPNEQVTCV DGTSRTLFVG
     TSQGRILLVD LPAKDVLNAL QLSVNAPVVR IVAATALDYL VVLSASTIFN IEIKTLKPIS
     SSAMSNIAHL ALNKDPVVAD PFALQFALVT NNRYILICEI KADNLVIQQE IRTDDNVVAL
     SYNKYCICYA LPNAYFVHNI LENKTLSLFP YDSQAIRPII INTDAEEFLV NSMQGLGVFA
     TSEGVSSRPP LFWGLTSIVS FTYRSPHVFV LTASSVTVYS SEQSVVLQRW PFTTGTLLEC
     IDGQMYICSS KNISYLEQIS WLDRAKALAD NGELDEALRF AENAVSNGQY DEDEILKFNE
     LKQKVALVLF KREEFEKFYE VAVSSELDPR AVLISFAFLL PFPSGFQSEL SKESTETLEK
     TFDDFVAEGS IELISFLEHY LRRIRKLHWT AGFRRDIDTV LLRLISLRKD ELGAEDMLLN
     FHCTFDDCNE WMRKHKRRKF LITIAFCLSN FDKALAISRE LYDENLWDDG IVRLCLQFFP
     RFYSEQTILG WVEFLLKIHQ DDAISGLKRC SIELDHSKIV RILQQDRSTL IKYLEGIKPL
     QIAEFHSMLF SMYADEINNL LGGDRRREKL YRKDLRTFLL QPSKLNLSDM RAVLEIWPHF
     AVELTLLEGV KENGSVACLE KLLNDHRDYD AAELFCIYTD TSEHVLQLTL LKFYLQNVTS
     QPEFGPRIIG LLNTSGLTSN KTEILQDIPK DWPLSSVLYF AEGAILSAKD RSHRQQLKKK
     SNMLPNGIFS VTTQALKALS REALRAAHLY IQIDEKTTCN TCGAPISNED AACQPHSRQI
     FHRRCLKS
//