ID A0A0N4TRX0_BRUPA Unreviewed; 245 AA.
AC A0A0N4TRX0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=ADP-ribosylation factor-related protein 1 {ECO:0000256|ARBA:ARBA00039478};
GN ORFNames=BPAG_LOCUS11379 {ECO:0000313|EMBL:VDN92565.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0001141701-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0001141701-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN92565.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Trans-Golgi-associated GTPase that regulates protein sorting.
CC Controls the targeting of ARL1 and its effector to the trans-Golgi.
CC Required for the lipidation of chylomicrons in the intestine and
CC required for VLDL lipidation in the liver.
CC {ECO:0000256|ARBA:ARBA00037377}.
CC -!- SUBUNIT: Interacts with SYS1. {ECO:0000256|ARBA:ARBA00038765}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290}.
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DR EMBL; UZAD01013227; VDN92565.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4TRX0; -.
DR WBParaSite; BPAG_0001141701-mRNA-1; BPAG_0001141701-mRNA-1; BPAG_0001141701.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR45909; ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1; 1.
DR PANTHER; PTHR45909:SF1; ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51419; RAB; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627}.
SQ SEQUENCE 245 AA; 27983 MW; 7A7A510557C0FF42 CRC64;
MTIHRCDYIF IYANFSFLKN FSDSGLYFFQ SCLVYKRGIK HTSNGKMYTL GVGIWERLRR
KSNYYIVIVG LDNAGKTTFL EQIKSRFIKN YQMLNPLKIT STVGLNGKMI CAGTIVLGSI
RLSFWDLGGQ EELQSLWHKY FEDSQALIFV VDSCDSDRFP EVSEAFKLVM NSEAVQKMPV
LVVCNKSDIE ECIGTEIIRV LTTDDRHRGD LALIPISALQ GLNIDRCMRW LCTVLTRNHS
ATDLS
//
