ID   A0A0N4U2C8_DRAME        Unreviewed;       655 AA.
AC   A0A0N4U2C8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN   ORFNames=DME_LOCUS5183 {ECO:0000313|EMBL:VDN55210.1};
OS   Dracunculus medinensis (Guinea worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX   NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000082301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:DME_0000082301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN55210.1, ECO:0000313|Proteomes:UP000274756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC       ECO:0000256|RuleBase:RU000394}.
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DR   EMBL; UYYG01001151; VDN55210.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4U2C8; -.
DR   STRING; 318479.A0A0N4U2C8; -.
DR   WBParaSite; DME_0000082301-mRNA-1; DME_0000082301-mRNA-1; DME_0000082301.
DR   Proteomes; UP000038040; Unplaced.
DR   Proteomes; UP000274756; Unassembled WGS sequence.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47969; CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED; 1.
DR   PANTHER; PTHR47969:SF29; KINESIN-LIKE PROTEIN; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Microtubule {ECO:0000256|RuleBase:RU000394};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|RuleBase:RU000394};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000274756}.
FT   DOMAIN          7..337
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
FT   REGION          368..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          399..518
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   BINDING         93..100
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   655 AA;  74581 MW;  F6289C8C594D46BA CRC64;
     MAEEVDNVRV IVRCRPLSEV ELENGFKSVV NIDHDSHSVC VSNPNAPQDP PRCFTFDSVF
     GEDADQLSIY NIAARPIVDN VLKGYNGTIL AYGQTGTGKT YTMSGRTDSL EHAGIIPNSF
     AHIFNSIAKC EQDKTFLVRV SYLEIYNEEI RDLLARSPMH RLEIKERNDI GVYVKDLSNV
     TVSSADHMQR LMNFGNSNRS VSSTKMNVES SRSHAIFTVT IECSELIDGR NHLTQGKLQL
     VDLAGSERQS KAESNGQRLK EASRINLSLS SLGNVISALI DSKAAHVPYR NSKLTRLLQD
     SLGGNSKTVM CANIGPASYN YDETISTLRY ANRAKNIKNV VRINEDPKDA LLRKFQLEID
     HLKKLLANEE SSDSDEEMGK KSEAKEMPKR QKGGYDERII ELEKNIELKR NELQRTKGLA
     EEERNILANE LQTREVELAR ARNEHEELVK KLKQLERKLI FGGENMLEKA EKQARLLEQS
     NAELDRAKAN EDHLRQALAE KNQERIDLEE KYNSLSEEAH GKTKKMKKVW NMLCTAKSEL
     SDLTIEHQRE IEGLLGSIRQ LKSELLLQLL IIENYIPPEY LELIEKFVSW NEEIGDWQLK
     CIAYTGNNMR ARNPLPVPVY KGEDPQMHDL FLSYSNEISL AYDSNRKLRS KKRRT
//