ID A0A0N4U2Q2_DRAME Unreviewed; 561 AA.
AC A0A0N4U2Q2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=B30.2/SPRY domain-containing protein {ECO:0000313|WBParaSite:DME_0000097201-mRNA-1};
GN ORFNames=DME_LOCUS5332 {ECO:0000313|EMBL:VDN55359.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000097201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000097201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN55359.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; UYYG01001152; VDN55359.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4U2Q2; -.
DR STRING; 318479.A0A0N4U2Q2; -.
DR WBParaSite; DME_0000097201-mRNA-1; DME_0000097201-mRNA-1; DME_0000097201.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
DR CDD; cd12872; SPRY_Ash2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.90.980.20; -; 1.
DR InterPro; IPR037353; ASH2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR10598; SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR PANTHER; PTHR10598:SF0; SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000274756}.
FT DOMAIN 260..460
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 173..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..216
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 63641 MW; 7828AA4623D76166 CRC64;
MRSKLTRTEL IKPVSSSVCY CDGKRELGSL ELFCAICRKC YGLSFMVCYV FNCGDCSPTK
SETWTPKQAN FVHMCVTVLA NLTYNVIKDK EDAIRDGVLV NPIFFNIESE IIPYFNAQWE
NLTSMTRRVK NTWHQTLLRA LTKETDLFET SEDGQSFALR ERDLLSIGPA HEPLKQIGKS
KGSGNISHRE CKDQERIDES SDGPKTRGSK RRNAEGGLNA LKKAKYTADY ASTRISGMAV
PIDFPFNREG YRYYLVEKDM SVPNREVFEQ EDIYGKPIPA HTYRITTHPT VTLSPNDRAF
QLKLSDDRLS VTGFEGYCVA RATHHISHGT YYYEVVFVSQ PPGSHVRIGW SQAVAPVQAC
LGYNQFSYSW RSLKGTVFHQ AKGKHYASGG FKEGDVLGCL ISLPSCPSDP NYDCMSVNSL
PQSSSYLFPS HKDLPLINFK HNYFYEEKDE IQNLIKDLKV ASGSYMDFLI RLQIEFFLNG
ISCGIAFRDI YAGFYFPAVS LFQSATVKCN FGPDFYFSLP DGAKAMCERV EEMQIEQTIS
DVLFLVENEK RLAEEARNYR S
//
