ID A0A0N4U5V8_DRAME Unreviewed; 180 AA.
AC A0A0N4U5V8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 03-MAY-2023, entry version 24.
DE RecName: Full=60S ribosome subunit biogenesis protein NIP7 homolog {ECO:0000256|ARBA:ARBA00018162, ECO:0000256|PIRNR:PIRNR017190};
GN ORFNames=DME_LOCUS6625 {ECO:0000313|EMBL:VDN56652.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000226501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000226501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN56652.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for proper 34S pre-rRNA processing and 60S ribosome
CC subunit assembly. {ECO:0000256|ARBA:ARBA00004087,
CC ECO:0000256|PIRNR:PIRNR017190}.
CC -!- SUBUNIT: Interacts with pre-ribosome complex.
CC {ECO:0000256|PIRNR:PIRNR017190}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NIP7 family. {ECO:0000256|ARBA:ARBA00009895,
CC ECO:0000256|PIRNR:PIRNR017190}.
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DR EMBL; UYYG01001156; VDN56652.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4U5V8; -.
DR STRING; 318479.A0A0N4U5V8; -.
DR WBParaSite; DME_0000226501-mRNA-1; DME_0000226501-mRNA-1; DME_0000226501.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042255; P:ribosome assembly; IEA:InterPro.
DR CDD; cd21146; Nip7_N_euk; 1.
DR CDD; cd21151; PUA_Nip7-like; 1.
DR Gene3D; 3.10.450.220; -; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR040598; NIP7_N.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR016686; Ribosomal_synth_fac_NIP7.
DR InterPro; IPR005155; UPF0113_PUA.
DR PANTHER; PTHR23415:SF4; 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG; 1.
DR PANTHER; PTHR23415; CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7; 1.
DR Pfam; PF03657; UPF0113; 1.
DR Pfam; PF17833; UPF0113_N; 1.
DR PIRSF; PIRSF017190; Rbsml_synth_fac_NIP7; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88802; Pre-PUA domain; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017190};
KW Reference proteome {ECO:0000313|Proteomes:UP000274756};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|PIRNR:PIRNR017190};
KW RNA-binding {ECO:0000256|PIRNR:PIRNR017190}.
FT DOMAIN 95..170
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 180 AA; 20349 MW; 4067822E9AA15E24 CRC64;
MRPLTDEETE IVFKKLAKYI GENVRLLIER GDSNYCFRLH KDRVYYCSES LMKKAACVAR
EQLLSFGTCL GKFTKTKKFH IHITALDYIA PYAKCKVWLK PNAEQQFLYG NNVVKSGIGR
MTDGALSHQG VVVYNMNDLP LGFGVTAKGT AECRKADPTA IVVLHQCDLG EYLRKEAFLT
//
