ID   A0A0N4UE28_DRAME        Unreviewed;       449 AA.
AC   A0A0N4UE28;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=FERM domain-containing protein {ECO:0000313|WBParaSite:DME_0000560901-mRNA-1};
GN   ORFNames=DME_LOCUS654 {ECO:0000313|EMBL:VDN50681.1};
OS   Dracunculus medinensis (Guinea worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX   NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000560901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:DME_0000560901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN50681.1, ECO:0000313|Proteomes:UP000274756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UYYG01000006; VDN50681.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4UE28; -.
DR   STRING; 318479.A0A0N4UE28; -.
DR   WBParaSite; DME_0000560901-mRNA-1; DME_0000560901-mRNA-1; DME_0000560901.
DR   Proteomes; UP000038040; Unplaced.
DR   Proteomes; UP000274756; Unassembled WGS sequence.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR014847; FA.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR   PANTHER; PTHR23280:SF27; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE; 1.
DR   Pfam; PF08736; FA; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   PRINTS; PR00935; BAND41.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM01195; FA; 1.
DR   SMART; SM01196; FERM_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000274756}.
FT   DOMAIN          9..315
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
FT   REGION          359..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   449 AA;  52381 MW;  F80900B925F1996D CRC64;
     MSNNLNRYIT CQITFLDNTQ HSFQIERHSK GQILLDKVFD YLELVEKDYF GLQFTSFVET
     NQIDAGIRVE DFEDTLRSSK CSTMNFQKWL DPTKSVRKQM LCPPFNLFFR VKFYVSDPVK
     LVEEYTRYHI FLQIKKDLYE GRLVCPENIC TILASYAVQS EFGDYCPEEH GDHYLNDFKF
     IPNQDNNFLS KVVDLHKIRK GQTPAQAEFN FLEVAKTTEL YGIELFNAKD EDGNSVNIGC
     CNRGIIIFRS NQQQNIFQWT TIMKLAFKKK LFSVYMKDEK SDDEIVRVFN MQNPEVCKVL
     WKNCIEHHTF FRLVAPPALP QKSFFNIGSR YRYSGKTEFQ SIEEMKRRAR VERSFQRFSK
     NPSRLTATNN GNGQYTQPAV TDNSSNVHSI SSSYNTTKQQ NTLLLLSLEA PNKMDMETIS
     PKSKRDLIPI LVEKQSSRKE VTSVDTVLR
//