ID A0A0N4UEG8_DRAME Unreviewed; 938 AA.
AC A0A0N4UEG8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE SubName: Full=Rho-GAP domain-containing protein {ECO:0000313|WBParaSite:DME_0000577401-mRNA-1};
GN ORFNames=DME_LOCUS768 {ECO:0000313|EMBL:VDN50795.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000577401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000577401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN50795.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYG01000008; VDN50795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4UEG8; -.
DR STRING; 318479.A0A0N4UEG8; -.
DR WBParaSite; DME_0000577401-mRNA-1; DME_0000577401-mRNA-1; DME_0000577401.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23179:SF3; RHO GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR23179; T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000274756}.
FT DOMAIN 101..283
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 412..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 605..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..636
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..747
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 938 AA; 107198 MW; B01ECA1294B86645 CRC64;
MKVMKKKIDN DRSASDVLDE LIKELELSLK EEFELIFDTG NSDFGSALKG PEIIFCLAIN
YINNSGFRIS ELQIERLDTF PLNRCRLILS TLNFSRANPA QTLNFFGRPL EGSAPPQPVL
TMIDHLLMSG LDVEGIFRKS PKQSTTRMLK AQLDRGSVPD FCQFSPHVTA ALLKEYLRDI
PGKLLLSGNY DLWASAMKLH EDEERKIVVK RLLQMLPSSH TVLLSAVLRL LRAITNSAHT
KMNARSLAVC IAPSLLDCPT MGRRAESLPQ LAEYLIIRAP ELLEPFQDAQ LAISSSLSND
SGLSDVDIPI ELINSISNSG NNNDKEKNSN ISSNTLTSSL SSALCASPQS LVTKYSHWKR
YSLRSPNSGY YTSSLSIDDE DIDMIVEDND RTPVLSRENS NIQRNIPIIR RKSSSKKERL
SERKAEIKRT SPLMKRSESI EVSFKQNNNY LPNTSECQRS TGVQGIQANS PILAHKQFYE
QSPLVKRKGS LKIKSFTADN DEQQGRSTDT SSSSYQAMRK SSLKESPRLQ RNRLLLLESF
YKNDSDSFED STTEDEFIQR ASLPRNIKFH TNNVKGDESI YTKYKYRFPI IASPIQYDRR
ILKREENRDP SENQESRTKA NIPNNSNNPL STTTSTTFPA TKWYHTANMQ VKEYRTEIKT
VAKEKFTPVL CVGPLRKKSE QGSVSELNSE LIETSHNLEL GQSTKAPLIR NQKDVNCKEK
SLNHLNELQT PLVHHEKTNS YQLAENRKVS EEPNRYVKSS YSYQSYPETQ KSNLRSLEKN
NYVEMDPSNH ESIKSLDRSN YYRSYQNNKN FSQNGIFKIE EASFSSIANG SLDNNERLIT
HDQDQADYQI GLHRNLRRIS TFHATDQFQT KKNKRSLSSE LLSNQDTDNK HKLRKNNRII
LMEPLEVNWS VNELKSIFQR NAHQPIRLDT EYRSKNHR
//
