ID A0A0N4UH99_DRAME Unreviewed; 303 AA.
AC A0A0N4UH99;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=CULLIN_2 domain-containing protein {ECO:0000313|WBParaSite:DME_0000691001-mRNA-1};
GN ORFNames=DME_LOCUS1524 {ECO:0000313|EMBL:VDN51551.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000691001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000691001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN51551.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
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DR EMBL; UYYG01000023; VDN51551.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4UH99; -.
DR STRING; 318479.A0A0N4UH99; -.
DR WBParaSite; DME_0000691001-mRNA-1; DME_0000691001-mRNA-1; DME_0000691001.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF76; CULLIN-5; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000274756}.
FT DOMAIN 1..161
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 303 AA; 35835 MW; 1830E89506D93632 CRC64;
MREMGMPAEY INKLYRMLQD IELSKDINNS FKKGIGKNKS ERNDLIESVS LKVLNAGAWS
RFGEKVQLQL PRELEDILPE VDEFYRKQHN GRKLQWFHHW SYGTVSFSNN VGKFDLDVTT
LQLSVLFCWN DRPHDQLSFE TLRIATQLAK ADLSRTLSWL VAFPKMKHQI LLTDCKSMNF
RDFTDSTLFW LNQQFAIYKN GKDHSRGRIN LIGRLQLSME QNSQDEHDDI LQLRAERIQE
AIVKIMKVRK RCPSAQLQTE LIELVKNVFL PSKRLFKEQI EWLIENKYIE RDPNDFNVFL
YVS
//
