ID A0A0N4ULD0_DRAME Unreviewed; 577 AA.
AC A0A0N4ULD0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Sorting nexin lst-4 {ECO:0000313|WBParaSite:DME_0000860001-mRNA-1};
GN ORFNames=DME_LOCUS2515 {ECO:0000313|EMBL:VDN52542.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000860001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000860001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN52542.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UYYG01000065; VDN52542.1; -; Genomic_DNA.
DR STRING; 318479.A0A0N4ULD0; -.
DR WBParaSite; DME_0000860001-mRNA-1; DME_0000860001-mRNA-1; DME_0000860001.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06862; PX_SNX9_18_like; 1.
DR CDD; cd11763; SH3_SNX9_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR019497; Sorting_nexin_WASP-bd-dom.
DR PANTHER; PTHR45827; SORTING NEXIN; 1.
DR PANTHER; PTHR45827:SF1; SORTING NEXIN; 1.
DR Pfam; PF10456; BAR_3_WASP_bdg; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000274756};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 11..73
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 372..482
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 224..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 65022 MW; 7B35204F978D4D2B CRC64;
MADFFNRASR HRMSQVRALY AFDAEPNSGE LSISVNEILT VIREGVEGGW LEGRNSKGQV
GLFPESYVTK ITSAPFSEML FSGKVRKTVE KYTSTKVSFA RITVETSDDD NENQKQNLNV
IFNNSLNPST FSRSTVICSS PKSNNDGKVK CRRNVNCSRI VGFNLPPMDD HPSSYLPAYS
LPPVNDDDWG IPPALAHKTT QNQPVRTTNE NENENATAVA LCEDFDDWTE DDEDDKDKIN
RKIGRSIGSA TLGSHTHSRG TSGSRTDVST DEETTTHSGE NRKQINVRKD LVVRNETGAT
TVSRSRSAGA EMITAKQVAT RMKNINRFSN FVKSGMESYL LGTAKMIAKP DEHHEIIMSS
SGPEWFPITQ SYTCIVDKPK KESKLKGLKS FIAYSVTSSL SGIQVSRRYK HFDWLHEQMS
AKYILIPIPP LPEKQVAGRY EEDLIEHRKS ILQIWVNKIC RHPVLSKSDV WIHFLTCTDE
KQWKNGKRKA EKDEYVGGNF LHCVTVPAQP LDSNKVEHQI ESFARCLRGL DESVRNIYER
ISERHKRLAG PYKSNWQKLA AAFAGLGHSF EHDALPR
//
