ID A0A0N4UME7_DRAME Unreviewed; 415 AA.
AC A0A0N4UME7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Zinc transporter 6 {ECO:0000313|WBParaSite:DME_0000901901-mRNA-1};
GN ORFNames=DME_LOCUS10565 {ECO:0000313|EMBL:VDN60592.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000901901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000901901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN60592.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterodimer with SLC30A5; form a functional zinc ion
CC transmembrane transporter. {ECO:0000256|ARBA:ARBA00038600}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane
CC {ECO:0000256|ARBA:ARBA00004166}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004166}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UYYG01001225; VDN60592.1; -; Genomic_DNA.
DR STRING; 318479.A0A0N4UME7; -.
DR WBParaSite; DME_0000901901-mRNA-1; DME_0000901901-mRNA-1; DME_0000901901.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR PANTHER; PTHR46531; ZINC TRANSPORTER 6; 1.
DR PANTHER; PTHR46531:SF1; ZINC TRANSPORTER 6; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00022906};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000274756};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022906};
KW Zinc transport {ECO:0000256|ARBA:ARBA00022906}.
FT TRANSMEM 16..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 368..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 45571 MW; C2F268F3472E7082 CRC64;
MGGLVIDWSN TNVRQACIGA AACVLCLFFL IGCVSVTRSL VLTSAAWLSV FSFFSLISSV
ISLSVTHKPS ASYTFGFARA PVLAVFSTTV LASLSSIFLV KECAEHLLEG DHHLHSQGLY
LFGAIAASVS LEIAAYGVRN QPIQHVITAS SSSSLQEHFA DVSHAICYLI PGLSAFLLPR
LNALTILAFL TSTACFITHW FSSELWWIDA ASALILSICV FITMWPLSKY TGRILLQTSP
PHVHNQLDRC ISEASTIDGV LELRNAHFWQ LDFLSMAGSV DVRVRRDADE QLVLTRVTEK
LSSVVSILTI QIVKDTGISW HNQNKAFISH ISSSPNLSTI NISPSGNENA ALISPQIYYN
SHHILHEHEH KHEHEHEHGH GHGHEHEHGD GHGHRHGHEQ VDGHGAVHDP HVTHH
//
