ID A0A0N4USF3_ENTVE Unreviewed; 633 AA.
AC A0A0N4USF3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Ribosome biogenesis protein BOP1 homolog {ECO:0000256|HAMAP-Rule:MF_03027};
GN ORFNames=EVEC_LOCUS18 {ECO:0000313|EMBL:VDD84875.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000001701-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000001701-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD84875.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC the large ribosomal subunit. {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC {ECO:0000256|HAMAP-Rule:MF_03027}.
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DR EMBL; UXUI01000008; VDD84875.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4USF3; -.
DR STRING; 51028.A0A0N4USF3; -.
DR WBParaSite; EVEC_0000001701-mRNA-1; EVEC_0000001701-mRNA-1; EVEC_0000001701.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR HAMAP; MF_03027; BOP1; 1.
DR InterPro; IPR028598; BOP1/Erb1.
DR InterPro; IPR012953; BOP1_N_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR17605:SF0; RIBOSOME BIOGENESIS PROTEIN BOP1; 1.
DR PANTHER; PTHR17605; RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN; 1.
DR Pfam; PF08145; BOP1NT; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM01035; BOP1NT; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03027};
KW Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_03027};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW Rule:MF_03027}; WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 48..308
FT /note="BOP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01035"
FT REPEAT 315..357
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 72236 MW; 7F4C3C5AECD8E754 CRC64;
MAKRSRAVKE VSSKEPETVK SARQIDDFDS SDEEGPRNTV GNIPLSWYAD CIHIGYDRDG
NQIMKKPKKD EIDLFLEKVE DPDYWRKVFD RDTGEYVKLN DEQVEQLLSI GSFKYAPGYD
PYEPFYEIFS SQTEIHPMSN RPLSKSSFLP SKSEAKLVDR MVYSIKMGWM KPKVAKSEKK
QVSDIWAEES EGPKTKSELA RLRMHFAAPK VGLPGHAESY NPPAEYLFDE DELRKYEETE
PEDRRINFIP QKYDCYRKVP SYDRFYNERF DRCLDLYLAP RKQKIKLNVD PSELLPKLPD
PQDLRPFPTT LAFYMRGHKG QVRSLSFEPS CGELLASGGE DCTLRIWSVS SGRCIIYFDS
SVNCVAYGPN KERTLIAVTV EAKKIFLVNA GEGDKSCVRN TQRFLDELDV EQSAVYGILF
QAAKQVIWHA NGNYFATFAP ECGSNAVCIH HVPTCKSQAP FARIKGVVTG VMFHPTLPHF
FVSTRQYVRI YDLKKCQLVK KVMTGSRWLS CMTIDIYGAN LFLGGLDRVF SWVDLDLSNK
PWKSFRHHRA AVRSIARHQK YPLLATASDD CSVLVYYARV TTDLQKDNEL VPVKRLIGHN
SINGLSVLSV VFHPSQPWLV TAGADGLVAL FSY
//
