ID A0A0N4USL2_ENTVE Unreviewed; 1117 AA.
AC A0A0N4USL2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=HMG box domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000011601-mRNA-1};
GN ORFNames=EVEC_LOCUS77 {ECO:0000313|EMBL:VDD84934.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000011601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000011601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD84934.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UXUI01000036; VDD84934.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4USL2; -.
DR STRING; 51028.A0A0N4USL2; -.
DR WBParaSite; EVEC_0000011601-mRNA-1; EVEC_0000011601-mRNA-1; EVEC_0000011601.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21990; HMG-box_CIC-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR13059; HMG-BOX TRANSCRIPTION FACTOR BBX; 1.
DR PANTHER; PTHR13059:SF16; TRANSCRIPTION FACTOR CAPICUA-RELATED; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 623..691
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 623..691
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 291..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1015..1035
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..901
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 902..916
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1017..1031
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1117 AA; 123624 MW; 35E64F1F796ED885 CRC64;
MPSRLIDQRY KKGEVVTTPG GIRKKFNGKQ WRRLCGKEGC NKESQRRGFC SRHLSLKGKA
ARNDSNVNTP LSTNNGTTVK NNCAMDWTPQ NIFTDFRGDG RVRPIEETDV ANTLLNLRNH
PGVPSFTTNL AETSFPLSAP PRLQQITAPG CLAPKVPRNS APSDLLNSFN EDCANEPEKI
FNRNALSLND ASSISCGSSA ENSPCETKVL HPQDLLPMIS VQKNSKKFYS MDNKPDPVAA
GLSPGIPFFL TQNFALWETF RLLSSNAEYM NKNGIGSNSA AATTIADIVN DSNNNDRDSL
SRGENIERQD EDGRNECGIT KSDASTASNI ENAAEVSEDG TIQETSIPKS LLFRKGELLH
AIISEDEDTS SSQNIKTGDT DEESSAATLG AIKKESKLRP TVPWHKLVPH LQMKVSEGVG
KGGSDSNSNV AQKNSQNGLG SSASSPDKNG KGNGSTSNDG HLNTGTVETS GQVLSHTVTD
TAMQLNLGGS FVNSNGNLLS HADVSAAGNI KSMANLTSSS YWESSVDTCK DTKGTKNRKP
FEDCTYSGKR KSDCTDAPDF ESFEGNGDSE AQNLSENPSN FPINETVGDC DDEIILCEDH
GLRSNRESSL SNLIGLLKVG DHIRRPMNAF IIFAKRNRPL VQERWPNRDN RAVSKILGQW
WYALGPEEKR KYHELATQVK EAHFRAHPGW KWCNRERRKI SSESRKENED IFLSQEVHYP
VLALAEKLED DSVSTSRVLP STVKTEELNL KQFSAPFVKD GPLKSPARAM EIRSPCLQSE
ATGNSPKIYG CSASYNSEFE HMVPASQEKQ QCNVGGFLAE SGNPLVKTEE KTYLESSATQ
PYLASKTLKV EKDCHSEESV IEKFVLMPTP AQRGIVKERR RTYEDYSEAK NFEESSRLET
GSDQTGEKVP ENSSLGCEKN SADANILVEK ACKESKVMLK SPTKKLFKRN DENMDRVLNQ
LDFEEKFACL PAFSPEDTIK VSGDAYSALQ NTYFFGANFS PSAVYNSIRQ SKEDLKKPSS
LYSPQTPSEK TGEKSVNRKL LDHKRQLIVE FLESYGMFPS GHSVSAFQSK NKQYFPNKQN
LTLKIREVRQ KMMAVVQSPI TPNGWLIKRI EFFNFVK
//
