ID   A0A0N4UZ62_ENTVE        Unreviewed;       880 AA.
AC   A0A0N4UZ62;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=SSD domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000289901-mRNA-1};
GN   ORFNames=EVEC_LOCUS2607 {ECO:0000313|EMBL:VDD87464.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000289901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000289901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD87464.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   EMBL; UXUI01007414; VDD87464.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4UZ62; -.
DR   STRING; 51028.A0A0N4UZ62; -.
DR   WBParaSite; EVEC_0000289901-mRNA-1; EVEC_0000289901-mRNA-1; EVEC_0000289901.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF185; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        261..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        412..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        506..524
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        715..733
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        739..760
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        767..788
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        808..830
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        837..857
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          269..440
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   880 AA;  100472 MW;  F6C60A9369502990 CRC64;
     MHGKLVGIYP LYFLIGSLLF TAICSFGFLN LTINLNLYKL FVPEDAPVRR EFERAKLYRE
     MPSGVDSSLA RPMHKRAVDS EIIRHDILRY YVVHKNYENL LKPEILTRLF NYSQEIFHVT
     TNYRGKTYSF DQFCSDDGSD GKCNNNLNIW LKHAGVLFSE NGIKTNPNLQ LSYPVMYLFN
     RPKDIGQVVY GVSVAGEKHE IVGAKVLTLH WSVHFPNTGE MNGAYHKFRD AVNDFWKSKT
     EECGINFIPH NDRAMDDEMR LIILTALPFA VPVSITLMVF VIMSNFSTKR VEYQFTSLFS
     ATINFFFLSK PMEAYLAVVS VILSLICTFG IVFTFGMAFN PVSCTMPFLI LAVGVDDAFL
     MLGAWRTTKR SLPPEERMAL TMAEAGVSIT VTSATNFGCF TLGYFLCATP AVASFCLLTA
     VGVIFDYLFQ ITFYSSIMIY GGRKEETGGL MGCCYRNKKV DDVSKSSNSI SAEKSHGRYL
     TAVFSSFFRL LGEYYAPLIL RDNVKIFSLF LFIAYFLLGV YGCSRIQVDI SPKKYIRDNS
     PMQTFIHLAD KFIWADNVMP TFYIMKPPDL RDPSARAQVN EIVYRLEHTK YSIGRVSTNF
     WMWEYQRFLN DYPGVDINRD FYKKEYLVDF LLQPDYAQYK EAVRIDHNTS NGEPCIIAFR
     FQTSYYGLDS WDKRQAELFY WRRLIAEYPE YDMFLADIFT PFLIDQRKSI APSSMQSIGS
     AIAVMAIIST FFLPDMQSVF FMTWSLLSIS MGVCAGLSLW GSDLDSVSTG CIVMAIGLAV
     DFSVHICYRY HRSEKRTAEE KVYDTLTVVA WPVLQAGLST LIGLCTLPLI PAYLIRVFYQ
     TVVLVNVIGL THALLWLPQL ISSLDSCDRV PLKLRYLNKQ
//