ID A0A0N4V3Q7_ENTVE Unreviewed; 736 AA.
AC A0A0N4V3Q7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE SubName: Full=FH2 domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000470201-mRNA-1};
GN ORFNames=EVEC_LOCUS4410 {ECO:0000313|EMBL:VDD89659.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000470201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000470201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD89659.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the formin homology family.
CC {ECO:0000256|ARBA:ARBA00023449}.
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DR EMBL; UXUI01007849; VDD89659.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4V3Q7; -.
DR STRING; 51028.A0A0N4V3Q7; -.
DR WBParaSite; EVEC_0000470201-mRNA-1; EVEC_0000470201-mRNA-1; EVEC_0000470201.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR043592; FMNL_animal.
DR PANTHER; PTHR45857:SF8; FORMIN-HOMOLOGY AND ZINC FINGER DOMAINS PROTEIN 1; 1.
DR PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000274131}.
FT DOMAIN 364..736
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 197..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 527..554
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 207..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 736 AA; 80746 MW; E9414BA6D19C0919 CRC64;
MLANGGTMAA TASGAGVSSV LNLRNGTADL AALLAASSSG TASADGNLPA ASGSLNPLAN
MNDAAALIGL SQLFAAQHHQ SLVQQFHAAA QQQQQNAQQQ LIHDKKRSYP CTFQFCVLCQ
KNVHSSKLPC HIRQCHVAKP MFQCPACDFT STYSKNNVKS HMVSLHGLAG DPISYMEQYA
GQVEEYMKKC FPHVRGRGRP IHGGGRVSPS SPSSPQSVES NGSRRGSFGS NNSSNTTSQR
QYTHSQRRMS AKQAAQQISL HEQLMAFAKA SQAQNLGSEN SATAAARAFQ GFDPATLLSV
SRPSATADIK TGVALKFEPS DTSLNNDMDT SVSSSANVVD EPVPSISTAS SNNGSNGTFD
VTSPVNECKS SPEIENIHRF RPGETLQPRW ELDWEVLTDE QTAQTVFDTF NTQSILEKLD
LTLFEPLLED STFLSEEKLQ KIADVRQRIH LQTFEIMFAV HRLDLAVLSA ENVDLVASIA
PSAVDILRFK NYEMSNSTST LGEDEQFILQ LSKIERMEEK LRAMSHMSHF SSRINKLNEQ
INDLMAAAKL LQNSSEFHNI VQLLLTYGNF VSGDFNAQLV KGFRTSCLLE LSMFKFPTMP
ETTLLNVVAE TISKHFPELA KFGEQIPIIE KAAKANFMSI ASTIRELETG HSRVLTEMQH
GGTIQLVADF IETAEPLLCD IKDAYNTVKN KLTSTLHYFG EPIPYEEIEL FQPEEFFSKI
AGFCRSLQKA LVDLHL
//
