ID A0A0N4V4H3_ENTVE Unreviewed; 735 AA.
AC A0A0N4V4H3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ENTH domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000502601-mRNA-1};
GN ORFNames=EVEC_LOCUS4710 {ECO:0000313|EMBL:VDD89959.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000502601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000502601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD89959.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SLA2 family.
CC {ECO:0000256|ARBA:ARBA00010135}.
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DR EMBL; UXUI01007936; VDD89959.1; -; Genomic_DNA.
DR STRING; 51028.A0A0N4V4H3; -.
DR WBParaSite; EVEC_0000502601-mRNA-1; EVEC_0000502601-mRNA-1; EVEC_0000502601.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd17006; ANTH_N_HIP1_like; 1.
DR Gene3D; 1.20.5.1700; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR030224; Sla2_fam.
DR PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR10407:SF15; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR Pfam; PF07651; ANTH; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF109885; I/LWEQ domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000274131}.
FT DOMAIN 10..139
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT DOMAIN 490..728
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT COILED 315..529
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 687..714
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 735 AA; 83186 MW; A2A616561FBF894C CRC64;
MSRSALVSTD RETFYKSQIV AVHKALNKNE VPLKPKHVRA LIVGTHRNKS SSIFWDTISR
IQLEKNPIVS WKFCHLLHKL IRDGHPKVVE ETRHCKQRIV QLGNFWQHLH TSSYGPANSA
YCKLLVNRLD FLERNHLFPG SLHLSETQMN TLVNGDVNHS FEVSIEMLDQ MDNLLHLQSI
VFDAMGVVHW NSLTPQGQCL LAPLILVIVD ASKFYDYLVK LIFKLHGQIS PDALSGHRER
FNDIFAKTKR FFELASNLQY FKYLVTIPNL PEQAPNFLRA SDLEDYQTPQ AVLHSDDVSE
SDTPPDGSSI ADESLVDARA RIEQYENRLQ QVKNENDHYK QTLDELKKEN DRLRAASVLS
ERHAVDETRL QDAEKRAQNS EQNFEKMKNA YTNLRQEHIQ ALKTVTNLQK ELANSEGEKL
NNEEAVNRLE RKVAEIEQEK ILAEEKAKGA LSAANDLQGQ LARCHTEIEN FTKNSLEKLE
ELCLKLPTSS TDVSNEQLGA LLEDEMKRMD EAIQKAVKML EEMQKKSRDT DTGVRLEVNE
KVLDSCNALM AAIMQLVAKS RAMQDEIVSL GRGTASPNEF YKRNHQWTEG LLSAAKAVGA
AANVLVYAFF TSDNAFEFLI VASQEIAAST AQLFVSSRVK ADRDSKRLAE LASASKAVNS
CTANVVATVK SGQQTLSDSQ NLDFSHLSLH EAKKEEMESQ VRTLELEADL MRERARFAAL
RKQHYHLASL VANEV
//
