ID A0A0N4V7K1_ENTVE Unreviewed; 575 AA.
AC A0A0N4V7K1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=WD_REPEATS_REGION domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000626901-mRNA-1};
GN ORFNames=EVEC_LOCUS5878 {ECO:0000313|EMBL:VDD91127.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000626901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000626901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD91127.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR EMBL; UXUI01008299; VDD91127.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4V7K1; -.
DR STRING; 51028.A0A0N4V7K1; -.
DR WBParaSite; EVEC_0000626901-mRNA-1; EVEC_0000626901-mRNA-1; EVEC_0000626901.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF68; FI02843P; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW Signal {ECO:0000256|SAM:SignalP};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..575
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033230252"
FT DOMAIN 296..357
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 384..416
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 519..550
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 85..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 575 AA; 63753 MW; D5B17F0D8BE6B362 CRC64;
MFLACRVWWA LVDTFNVTWG ETFCPLEDPA VFGFVVPDLL SERICIASCQ YTLVMSGLQN
RTLSSSSPMR EIQSRINDMT VTSKTPGAND RCMKTPSSSK RNDGFLIRQK TPNNNAGHSK
AKGRLKQREV TPSRNPNYCG TVGGGDRFIP NRSATQFDFA NHCLSQSSLL NTSSSAPVSP
VKAEKEIKKQ LMRAKSGSDI NCEERILMYK KGQAPAAPLG YMHHPKVLYC SGVNAAGSVR
KGLRHIPCSP ERVLDAPNLM DDVYLNLMDW GQNNVIAIAL TQTLYLWNAE TGDIATLFEL
PEGERLYVSS VQWSADAAYI AVGMSNGEIR LFDPTRETAL RKMQVQINRV GSLAWRQHIV
SAGCRSGRIY HHDVRVAKHH IGTFENHAQE VCGLKWSPDL HYLASGGGDN IANVWEPNMI
SAEEPVPLYT LDEHLATVKA IAFNPHKSYS LATGGGINDR CIKTWNLTTG TLCRSEQTDS
QVNGIAFSQH YDELISAHGY PSNLLRIWRN STMTCIQELT GHSDRVLGIT VSPDGQLVMS
SSADESLRLW ACFKVDKSMN HKERTKSSRL LAAVR
//
