ID   A0A0N4VAQ6_ENTVE        Unreviewed;       700 AA.
AC   A0A0N4VAQ6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 2.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Acetoacetate--CoA ligase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EVEC_LOCUS7073 {ECO:0000313|EMBL:VDD92322.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000757101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000757101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD92322.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UXUI01008763; VDD92322.1; -; Genomic_DNA.
DR   STRING; 51028.A0A0N4VAQ6; -.
DR   WBParaSite; EVEC_0000757101-mRNA-1; EVEC_0000757101-mRNA-1; EVEC_0000757101.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131}.
FT   DOMAIN          55..111
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          148..487
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   700 AA;  78918 MW;  5362A7E17043EE73 CRC64;
     MDADHLYYRP PTEQTELKKL PIMRFMNYLD TEYNVKFNAA CVVNMFYALF IADSYWELHQ
     WSCDHYETFW EAVLRFTKII LKKRYTKVVE AKDFDQIPQW FIGAELNYAE NLLFAHGGNL
     DDGDKQFFCR LVTQNGVIGF FLVSETKFAT YSYQQLRGDV IGTATALKSL GVSPGDRVVA
     YVSNCYETTV SALATAAIGA AWSSASVDFG TFGVLERFSQ VSSLPSLRHV ILLNHLKEDL
     PKHLITNVRY TTLRNLQAFG EGKSFEFASV PFSHPLYIMF SSGTTGSPKG MIHTCGGTLL
     KHVEEHILQT GFTKNDTILF YTTCGWMMWN WLMSCFYIGM TVVLFDESPL EPDCHILLKI
     AARHKCTVLG MGAKIYDEYR KRGGRPASLY ELSSIRMFLS TASPLNRDSF QFLNESVRPG
     ALIGSISGGT DIVGCFMGSS EILPVTEGEC QCPYLGIDLA AYVDDEGNYK KGKCVLGKQG
     ELVCKKPFPS MPCEFINDPD RIRYHQTYFE RFEGVWAHGD FCQINPTTGG IIMLGRSDTT
     LNRGGVRIGT AEIYTVVQRF PAIEDSLVXX XXXXXXXXXX XXXXXXXXXX XXXXXXXNQI
     ASMVRCWVLL FFHTSWSDIK PLRDCGSDEK ILLFVKINPA HLLTESLKKE IKMEIRSEMS
     PRHVPDDIIA VPDIPYTVNG KKVEMAVKQI LNGQKVSYLL
//