ID A0A0N4VBP4_ENTVE Unreviewed; 870 AA.
AC A0A0N4VBP4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Protein kinase domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000795801-mRNA-1};
GN ORFNames=EVEC_LOCUS7442 {ECO:0000313|EMBL:VDD92691.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000795801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000795801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD92691.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UXUI01008925; VDD92691.1; -; Genomic_DNA.
DR STRING; 51028.A0A0N4VBP4; -.
DR WBParaSite; EVEC_0000795801-mRNA-1; EVEC_0000795801-mRNA-1; EVEC_0000795801.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR23257:SF975; DUAL SPECIFICITY PROTEIN KINASE SPLA-RELATED; 1.
DR PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR01415; ANKYRIN.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00248; ANK; 10.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 7.
DR PROSITE; PS50088; ANK_REPEAT; 7.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REPEAT 117..149
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 154..182
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 183..215
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 216..248
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 249..281
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 287..308
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 376..408
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 556..823
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 583
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 870 AA; 95679 MW; 3AC30023BE4FA9E0 CRC64;
MGNYKSRPSS TCAEELKKKI SEGYAVIRSR LSDDVKPRFD VWNAAQCACF QGDLKSLEGQ
LTNVSLDERT EDRLLSPLHL ICAGHSEQQA EKVAFLLDKC GDDDAKRRAL LCHLTRNGFS
ALHFAIYKSE VETVNILLNN GADVNLAGRL QLPPLHLAAM CGNVELIKQL LTKGASLHST
DFVQYTALHC ATYSSHDKAV RLLLSYGADP NYSGGVQDRP LHLASGKGNL EIVSALLDAG
AYPSLTDDEG NTSLHFAART GNVGVIDLLL MKAGNAKQEL ALKSNIYGDT PLHLACYAGR
LEAAKRLIAI SGSSTLSLVN LVCNVVVCMY KQLHDLQENV FSETPLHAAC TSGRNMELVA
YLLRQPGVDP NFQGQDGHTA LHSACYHGHL HLVQFLLDSG ADQSLTARAV DNPLSPSGSV
GSLTLASVRA QTMFSLSRPE SAGSIGDSLM SSTQSLYDDQ QQTPIIWAYE KGFDQIVALL
KHYANKRPDS DVCSEYSSGD SSYTPLPSPM GRLHSMTKEK AEILQLRASL SSTFRLSLND
VDFQDSQKIV VYVHAIVVQD AIGSGSFGKV YKGTYKGTTV AIKRYRPVAF GAKSEVDMFC
REVSILRMLQ HPNVIAFIGA CLDDPSQFAI ITEYVTNGSL FSLLHEQKRV LEMALRLNIG
VDVARGMRYL HELATRPVIH RDLNSHNILL HENGRAVVAD FGESRFMAQR DDDNMTKQPG
NLRWMAPEIF TQSGRYDRKA DVFSYALCVW EIHAAELPFA YLKPAAAAAE MAYKRGRPSI
PPHPTPQFPA HILKVIVSAW QHNPDARPDF AEILPTVEAH VTSLNISECS LAVMKQTGRS
PPSSVSLLKN HWERRSTNSK WFLQQKVSTV
//
