ID   A0A0N4VFD1_ENTVE        Unreviewed;       516 AA.
AC   A0A0N4VFD1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Fork-head domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000944801-mRNA-1};
GN   ORFNames=EVEC_LOCUS8858 {ECO:0000313|EMBL:VDD94107.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000944801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000944801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD94107.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR   EMBL; UXUI01009652; VDD94107.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4VFD1; -.
DR   STRING; 51028.A0A0N4VFD1; -.
DR   WBParaSite; EVEC_0000944801-mRNA-1; EVEC_0000944801-mRNA-1; EVEC_0000944801.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR018122; TF_fork_head_CS_1.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR   PANTHER; PTHR11829:SF380; PROTEIN FORK HEAD; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00657; FORK_HEAD_1; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..516
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033720932"
FT   DOMAIN          162..259
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        162..259
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          107..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          264..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          307..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..346
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        353..396
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   516 AA;  56452 MW;  0528413F1C34687A CRC64;
     MNLMLNGTGG LAAASAVSAA TLDSSALYQA QTATISQGMT AQDYAVVPTY STALNAYNQY
     PYQTSNSLTA NGTLNSYYTS NYMNPNSQVQ QTYNGFGVTG GISPIGNSSR NSSNANSSTV
     GSTSSSSQIS PNCRTGRVSF NEQTQNELAQ MRNYNGKIGT AKPPFSYISL ITMAIQRSES
     RMLTLSEIYQ FIMDNYAYYR QNQQRSAGWQ NSIRHSLSFN DCFVKVPRTP DKPGKGSFWT
     LHEDCGNMFE NGCYLRRQKR FKIGEGKPRN KKNGHRGSSN SNNANTHVKE ENDTEYDAKN
     LLSNNEMKMS PSSQQSSQAG PQPAQTQQQQ PPTACSPTSE LTSYDFFKSE THGAPGEQSN
     LQRQGGLQNS STTQQQTMQS QMQLSATSSM PTSVANSQPT SVISAVGSVP VSHFYLKSEQ
     KKKFFFYYTI TAVQMTYGGQ YPAFGIYSNG SVSTFGDLSQ TSLPGLNSGF RIGNLIDNCS
     NVYNSVYATQ PTTNLAEYPY QQTLYSSNNP NSLPNL
//