ID   A0A0N4VGG9_ENTVE        Unreviewed;       821 AA.
AC   A0A0N4VGG9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=valine--tRNA ligase {ECO:0000256|ARBA:ARBA00013169};
DE            EC=6.1.1.9 {ECO:0000256|ARBA:ARBA00013169};
DE   AltName: Full=Valyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00029936};
GN   ORFNames=EVEC_LOCUS9265 {ECO:0000313|EMBL:VDD94514.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000988001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000988001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD94514.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363035}.
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DR   EMBL; UXUI01009927; VDD94514.1; -; Genomic_DNA.
DR   STRING; 51028.A0A0N4VGG9; -.
DR   WBParaSite; EVEC_0000988001-mRNA-1; EVEC_0000988001-mRNA-1; EVEC_0000988001.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004832; F:valine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006438; P:valyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd07962; Anticodon_Ia_Val; 1.
DR   Gene3D; 3.40.50.620; HUPs; 2.
DR   Gene3D; 3.90.740.10; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002300; aa-tRNA-synth_Ia.
DR   InterPro; IPR033705; Anticodon_Ia_Val.
DR   InterPro; IPR013155; M/V/L/I-tRNA-synth_anticd-bd.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   InterPro; IPR009008; Val/Leu/Ile-tRNA-synth_edit.
DR   InterPro; IPR002303; Valyl-tRNA_ligase.
DR   NCBIfam; TIGR00422; valS; 1.
DR   PANTHER; PTHR11946:SF111; VALINE--TRNA LIGASE; 1.
DR   PANTHER; PTHR11946; VALYL-TRNA SYNTHETASES; 1.
DR   Pfam; PF08264; Anticodon_1; 1.
DR   Pfam; PF00133; tRNA-synt_1; 1.
DR   PRINTS; PR00986; TRNASYNTHVAL.
DR   SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   SUPFAM; SSF50677; ValRS/IleRS/LeuRS editing domain; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363035};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363035};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363035};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363035};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363035};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131}.
FT   DOMAIN          58..647
FT                   /note="Aminoacyl-tRNA synthetase class Ia"
FT                   /evidence="ECO:0000259|Pfam:PF00133"
FT   DOMAIN          694..790
FT                   /note="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase
FT                   anticodon-binding"
FT                   /evidence="ECO:0000259|Pfam:PF08264"
SQ   SEQUENCE   821 AA;  93268 MW;  550C9F68188CCD09 CRC64;
     MFEVVRRNST GIVGRRWFFG INGAKLVSSL PSKSFDLREV VASYNPQSPN NSVISALDEK
     REVFKLALPP PNVTGRLHLG HALTAVVEDA ICRYERLCGN KVVWYGGFDH AGIATQAVVE
     KQLWIKKRIR RHLLSDEEFL AHCTEWKENR VYDMKKQFCD LGIMLDMEAA YYTMDERFSK
     AVRRAFVELH SSGNIFRAQR MINWCPSLQS ALSDEEVNHI SLEDLNEISV PHKDGMRKIK
     VGQMHKIAYE LLSRRERVEV ATTRPETLFA DVALAVNPCD SRYCHLIGEM VRHPLVHSRI
     LPILGDEAVV PDKGTGVLKI TPSHDFLDFE IAQRHLEKLP DDIMNYSCID EMGKLVNAGD
     FDGQDRFDVI EKLRAVNAYD GIMKHDKGSI AVCSRTGDVI EPMVKDQWFL DCSQMNRRLL
     EAVENQKIIV KPSFLTSKLV EWLQNNEPWC LSRQITWGHR IPAYLSGNKW FVAESAEEAE
     KVSGKSLMEK TLVQDNDVLD TWFSSSLVPL VLAGWPEKRV NSHCLSLMET GYDIVGFWVV
     RMLTVCEQLC GHYPFDKIFL HGLIRDSKGR KMSKSLGNVI EPGDVIDGRS LEEMLERVEL
     SSLPDHEKSE AKQEVRNEFP NGIQKFGADA LRFALLRHDI TGLDINVDIV ETASEGYRFC
     NKLWNLCNYS LMVFAASPGS SVPSSSSASA NIADRWILSR LGSVLLDFGP QIKGFTPHHA
     ATGLQKFIQG ELCDFYLETT KKALREKDQK RLAEIADTLR LVLHNSLAAL SVIMPFISNY
     LFEKVKVDDS FKLDCFILQK VRFSFMLLSC SLLVFFRTSH F
//