ID   A0A0N4VMB1_ENTVE        Unreviewed;       452 AA.
AC   A0A0N4VMB1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=GpcrRhopsn4 domain-containing protein {ECO:0000313|WBParaSite:EVEC_0001206201-mRNA-1};
GN   ORFNames=EVEC_LOCUS11307 {ECO:0000313|EMBL:VDD96556.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0001206201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0001206201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD96556.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; UXUI01011860; VDD96556.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4VMB1; -.
DR   WBParaSite; EVEC_0001206201-mRNA-1; EVEC_0001206201-mRNA-1; EVEC_0001206201.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR   InterPro; IPR047831; GPR180/TMEM145.
DR   InterPro; IPR019336; GPR180/TMEM145_TM.
DR   PANTHER; PTHR23252:SF45; GPCRRHOPSN4 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR23252; INTIMAL THICKNESS RECEPTOR-RELATED; 1.
DR   Pfam; PF10192; GpcrRhopsn4; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..452
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033230478"
FT   TRANSMEM        188..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        223..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        352..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          155..395
FT                   /note="GPR180/TMEM145 transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF10192"
SQ   SEQUENCE   452 AA;  52924 MW;  619C8DC2524AC9D1 CRC64;
     MLPLWLSASF LCQFKVIAKF GFQQLHHLDK ESTSLVYSNR SISDRQAVLI AVPQARISDF
     YSNSVYGQTC DSVLSKINTI VFDRHCFPNG TSDLIRWVPC QKGSICNETS KEKVNHGYQL
     TLRIEQLDTP QYWYVILMKC TLNENCSWVP PRKNIDLNYD LWLTNGNPMS KNTDLFSYQF
     SFDEQDTILI YFAALVMYLT LSLFEWRAVV TRKQTYISSK QKLLCLILFT KILGLFLQTL
     NIIVFAYDGR GLFVARFLGE FFRLFAVCIL YLLLILLSRG WSINDYGKSA LNRTVIVFFV
     VDILHDIDVF KSWPGYGMLL IRMCQALWFL TEIRYTIRRY LLFFIHLTFR RILFYYVVVF
     FFFSERVIVS FISVLWRFKV ILAITTFANF IAICSLVHLF WPTGSYSRFF TAANNPHRRL
     DSVNSAELRD MEYLLQDSDS DSESLVLDLR SI
//