ID   A0A0N4W0X9_HAEPC        Unreviewed;      1408 AA.
AC   A0A0N4W0X9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=DUF3591 domain-containing protein {ECO:0000313|WBParaSite:HPLM_0000325101-mRNA-1};
GN   ORFNames=HPLM_LOCUS3243 {ECO:0000313|EMBL:VDO20453.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000325101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0000325101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO20453.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO20453.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF1 family.
CC       {ECO:0000256|ARBA:ARBA00009064}.
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DR   EMBL; UZAF01016105; VDO20453.1; -; Genomic_DNA.
DR   STRING; 6290.A0A0N4W0X9; -.
DR   WBParaSite; HPLM_0000325101-mRNA-1; HPLM_0000325101-mRNA-1; HPLM_0000325101.
DR   OMA; QLHWEDS; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0001091; F:RNA polymerase II general transcription initiation factor binding; IEA:InterPro.
DR   GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd05511; Bromo_TFIID; 1.
DR   Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR   InterPro; IPR001487; Bromodomain.
DR   InterPro; IPR036427; Bromodomain-like_sf.
DR   InterPro; IPR018359; Bromodomain_CS.
DR   InterPro; IPR040240; TAF1.
DR   InterPro; IPR022591; TAF1_HAT_dom.
DR   PANTHER; PTHR13900; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR   PANTHER; PTHR13900:SF0; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1; 1.
DR   Pfam; PF00439; Bromodomain; 2.
DR   Pfam; PF12157; DUF3591; 1.
DR   PRINTS; PR00503; BROMODOMAIN.
DR   SMART; SM00297; BROMO; 2.
DR   SUPFAM; SSF47370; Bromodomain; 2.
DR   PROSITE; PS00633; BROMODOMAIN_1; 1.
DR   PROSITE; PS50014; BROMODOMAIN_2; 2.
PE   3: Inferred from homology;
KW   Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT   DOMAIN          1152..1222
FT                   /note="Bromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50014"
FT   DOMAIN          1274..1329
FT                   /note="Bromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50014"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          219..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          842..878
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1388..1408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1408 AA;  160967 MW;  635E832455CD7538 CRC64;
     MEVDETLVNG HASTSGIKEE KMEDGEWDPD EGMSDFYRHH PCARNERTPK TPFVPPSKRD
     DAPLASILNP QLDNIDPRRF FADYELDSVV RFSRIFASNI KSSSKAEIWW PSKTFHKKVS
     AEVGVLDELK YGVEPACGWV PTQYTRTYEQ YMLAVKNDAF DLMFQPIQKG ITPSPITLAP
     YLVFFVSKYF LFYLFLFLSE PKVLSLDYLD DPLIYGMPDD RRSDDPMDST PNKPFDRKEH
     QFTKKSKMIL GQVQQRQKQE EEEQMETSVA QMTDKDPFNL SNDDYYLPKA VNKSGPAGNS
     MLIQHSIPAQ NIHRTFFPTF LIPSKLRHFH RQPLSKRVIR HLFIGDLTGR FLQQREKQRC
     AEGGGDIFFM RDVADLSGRD GDLVLLEYSE EHPPLLCQPG MASKIKNYYK KVKERDSDVD
     PDFEFGDMAY LHTVPFLGQL QPGQAMQSIE NNLFRAPIYR HAPQHTDYLL IRNRNGWFIR
     PCPPSFLVGQ QCPLYEVPSP NSKRATIFVR DFLLAFIYRL FWASEHRPRR LKMDDIKAAF
     PHYAESSVRK RLKQCSDFKR LGTGPDQNYW VLRPEFRLPS KEEVLAMVTP EMCCAQYSML
     AAEQRLKDAG YGEKYFFTPE NEDDSDDQVT IEDEIKCAPW NTTRAFLSSM RGKCLLDQTG
     IADPTGCGQG FSYVRVSQKP QKDDTPAMPK RLVTGTNADL RKLPLKEAKE ICRDYGVREE
     EINALSRWEI IDVIRTLSTQ AAKAKADSSG DQGNVSGMAR FARGNIRFNF ADMQEKYKKH
     CQHIFDLQNQ TLANPEALST DEGSSGEDSD NEELATRLET MLQANKGKKH ISMSERARME
     FENEEKERQD LKRMVHGDAT NKTEKDKKEA TAEEKKNVSK IGEDLAASAS KISGITANQK
     LKIYRTMKNP DGTESTRVEV VTRPQLIEAY TRIRMTKDEN FIEVYAQMDE QFKEVGRVKI
     TDLCVLFSFP SRRGESRSAR VIEKKPIPIK PNLQKMRCSA CHGTGHMKTN KNCPLYGKDS
     SKTPGKETDE PASLTGELVA VEGTKVKISR KVINHEQPAK KKKIKQDHER QESICVVPSG
     IIDALLGIIY FPAVTPRPRL NAGAGVASAK RRASTLPEED YLQGPHKSVQ RIRADPKVTM
     GTLLTEIVNE LKTIPGSEHL MFAVNAKKVK DYYDIIKNPM DLQKIKSKIA DNKYELRQEF
     LLDVKRMLDN SRLYNGDNHV ITDAAKKMFE LASKRLVEKE QQLMKLEKAI NPLLDDNDRV
     GFGFVLEKIV QACKNIPKSV PFHTRVDAKK VPFYYQKISR PMDLGTIEAN VKAYRYVTVQ
     EFRDDIHQVG ERESVVTFPF PCFILSLTIL RLNCIITDES AWTNELLQSR MHSSGQLNND
     LALSDSDEEE RMEAIKRGDT SDNLLDSF
//