ID   A0A0N4WK80_HAEPC        Unreviewed;       328 AA.
AC   A0A0N4WK80;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=7TM_GPCR_Srx domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001147001-mRNA-1};
GN   ORFNames=HPLM_LOCUS11462 {ECO:0000313|EMBL:VDO42934.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001147001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001147001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO42934.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO42934.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAF01017576; VDO42934.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4WK80; -.
DR   WBParaSite; HPLM_0001147001-mRNA-1; HPLM_0001147001-mRNA-1; HPLM_0001147001.
DR   OMA; ITIDCAV; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR019430; 7TM_GPCR_serpentine_rcpt_Srx.
DR   Pfam; PF10328; 7TM_GPCR_Srx; 1.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        231..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          105..248
FT                   /note="7TM GPCR serpentine receptor class x (Srx)"
FT                   /evidence="ECO:0000259|Pfam:PF10328"
SQ   SEQUENCE   328 AA;  37501 MW;  893C4DD6809760AC CRC64;
     MMGDSSPRNP AKVLPYFICD TMSDIVGLLL CGVTIYGVLS SKKIFPIFTF IATVFCSATS
     LLLLQDLGLN ILLLDYLLND FSFKIPSWQQ NLSLFLAGLI RFVRFFLTML QMLMTVNRLC
     AVLLVTRYQR IFTFRNTITA VVVFLLLSAP PLPIFIFRLG GCTAYFVPEV LGYRYASSKC
     VSTIDFILAI FRLTMFSIII TIDCAVCYIQ YRRRNKNRNA QGKQGSQSAE LQFVLMTVIL
     AALSGLSTVL RKLVDHMDWI TVGFINRQIR KEVLDLLCFW KRKQTMRLVT SMPNVAHMRV
     MKHHCLMPSS RRKTYANIQP CRCKVDNT
//