ID   A0A0N4WKW3_HAEPC        Unreviewed;      1306 AA.
AC   A0A0N4WKW3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Chorion peroxidase {ECO:0000313|WBParaSite:HPLM_0001174501-mRNA-1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001174501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001174501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   WBParaSite; HPLM_0001174501-mRNA-1; HPLM_0001174501-mRNA-1; HPLM_0001174501.
DR   OMA; MYTIWMR; -.
DR   Proteomes; UP000038042; Unplaced.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   CDD; cd09823; peroxinectin_like; 2.
DR   Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 2.
DR   InterPro; IPR019791; Haem_peroxidase_animal.
DR   InterPro; IPR010255; Haem_peroxidase_sf.
DR   InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR   PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR   PANTHER; PTHR11475:SF131; PROTEIN CBG17660; 1.
DR   Pfam; PF03098; An_peroxidase; 2.
DR   PRINTS; PR00457; ANPEROXIDASE.
DR   SUPFAM; SSF48113; Heme-dependent peroxidases; 2.
DR   PROSITE; PS50292; PEROXIDASE_3; 2.
PE   4: Predicted;
KW   Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2}.
FT   REGION          501..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..519
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         1013
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ   SEQUENCE   1306 AA;  146401 MW;  C5D505517CA6A0AE CRC64;
     LPSASDVAAL FTPAPRGHAT CSLMLAQWAS FIYDDIAHVA TNQLVKEGFF PGSKHLPLPC
     CSSSTNHPEC FPIIAADGKC VSYSRSLPAP RENCSLGPRE QGNTVSGYLD ASQIYGSSQE
     IVDKMRSFKD GLLNLRILSA SHGGLPQADD DEDCKSRTLS SEPCFMAGSS RINLLPSNAV
     MYTIWMRQHN LIAGKLKEVN PVWSDEKLFQ EARRIVIAQI QHITYNEFIP VIVGKENLKR
     YALDLQVNGY DSRYDMKVDG STLNVFAAAV GQFFLTLLPD KITVIDSFGN TKREDPLGRV
     FNDPSFIYQR NRLDAVLRFL TRSPIMKPGL HMTPELKHAF KRGIGTGEKG IDMAAQIIQM
     GRDHGIPGYL EWRRHCQLDN VQSFASMSAR LLPSVNASLF EQLYESPEDV DLIVGGLAEA
     PLPGSLLGPT LSCLFAKQME KTKRGDRFWY ENFFYPSAFS TSQLEEIRKT TLARIICDNS
     DDLRFIQHNV FSLQDEYGSH AGDDFSESGN KEKKEEMGRN CPVSCSSSVI DSIDFSAWKD
     EEPKRALPIT KATLEKAIRL GIEQYNRLQA AEGRRIRAQG PPPNAAGQSA VFTHAALMAP
     KRESIDIART AGVLREATQV LIKGTGLNEG ERLPLGLDVS TLQQLLPDVE VESIIGNFTP
     FLGHDPLPKE QCLPQPLPCD HTSKYRSYSG WCNNLQFPKY GNAFVGMRRL LDPAYDDGFD
     APRTKARSGG ELPSARVVSN VVHNDAPEFH VRFTHMLMQF GQILDHDMMH SPIARGPNNT
     ILNCSSCDSQ ERLSIHCFPI KIGKDDPFFP ATHQDGRPRC MPFTRSLLGQ LTLGYRNQLN
     QLTAFLDASS VYGSTECEAN QLRLFSMGKL NFTDLGFNKE ALPQGRQERD CRSVLSSTQK
     RCFVAGDERN NEQPGLTVIH TILLREHNRI ASQLRRVNNF WTDEQLYQEA RRINIAKLQH
     VIFKEWLPVV LGCETMAKYD LMPKKSGYFT GYDPHCDPAI SQEMSTAAFR FGHTLIRAKF
     PRLTDTYRNM SDDDHFSDPS PLYERQNGHL ESMLMGLIGS ESMAFDRHIT NAVRNHLFAK
     PGGPLTGIDL PAVNIQRGRD HGVQPYNKYR ALCGLRPAQK FDDLRSTMDD SAVEALRKVY
     EHVDDIDLFP GIMSERSMKD QLAEIRKTTF AKIICENSQF ARKIQPNVFL MADELTNAPT
     SCSELPDTDL FEWLDREYCL VDHRVINLGK TKRITPCVTC TCTREGPECH SITIDHCDRL
     FDDYLASEIA KVGMLLQPED RLRAKAFLGS GLRDPMCSIC QGASSE
//